| Tag | Content |
|---|
| CPLM ID | CPLM-021726 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Spliceosome-associated protein CWC15 homolog |
Protein Synonyms/Alias | Embryonic development factor 1; mED1 |
Gene Name | Cwc15 |
Gene Synonyms/Alias | Ed1 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 18 | PARGGRGKGEGDLSQ | acetylation | [1] |
|
Reference | [1] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways. Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y. Mol Cell. 2013 Jun 27;50(6):919-30. [ PMID: 23806337] |
Functional Description | Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing (By similarity). |
Sequence Annotation | MOD_RES 2 2 N-acetylthreonine (By similarity).
MOD_RES 24 24 Phosphoserine.
MOD_RES 110 110 Phosphothreonine (By similarity).
MOD_RES 121 121 Phosphoserine (By similarity). |
Keyword | Acetylation; Coiled coil; Complete proteome; mRNA processing; mRNA splicing; Nucleus; Phosphoprotein; Reference proteome; Spliceosome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 229 AA |
Protein Sequence | MTTAARPTFE PARGGRGKGE GDLSQLSKQY SSRDLPSHTK IKYRQTTQDA PEEVRNRDFR 60
RELEERERAA ARDKNRDRPT REHTTSSSVS KKPRLDQIPA ANLDADDPLT DEEDEDFEEE 120
SDDDDTAALL AELEKIKKER AEEQARKEQE QKAEEERIRM ENILSGNPLL NLTGPSQPQA 180
NFKVKRRWDD DVVFKNCAKG IDDQKKDKRF VNDTLRSEFH KKFMEKYIK 229 |
Gene Ontology | GO:0005681; C:spliceosomal complex; ISS:UniProtKB. GO:0003723; F:RNA binding; ISS:UniProtKB. GO:0000398; P:mRNA splicing, via spliceosome; ISS:UniProtKB. |
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