CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-010133
UniProt Accession
Genbank Protein ID
 U00089 
Genbank Nucleotide ID
Protein Name
 Ribonuclease J 
Protein Synonyms/Alias
 RNase J 
Gene Name
 MPN_280; A65_orf569, MP555 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mycoplasma pneumoniae (strain ATCC 29342 / M129) 
NCBI Taxa ID
 272634 
Lysine Modification
Position
Peptide
Type
References
3*****MIKDFDPSEFacetylation[1]
114IAASLILKKVNEHKDacetylation[1]
554TVSYFIWKNKSRNPLacetylation[1]
Reference
 [1] Cross-talk between phosphorylation and lysine acetylation in a genome-reduced bacterium.
 van Noort V, Seebacher J, Bader S, Mohammed S, Vonkova I, Betts MJ, Kühner S, Kumar R, Maier T, O'Flaherty M, Rybin V, Schmeisky A, Yus E, Stülke J, Serrano L, Russell RB, Heck AJ, Bork P, Gavin AC.
 Mol Syst Biol. 2012 Feb 28;8:571. [PMID: 22373819] 
Functional Description
  
Sequence Annotation
 METAL 81 81 Divalent metal cation 1 (By similarity).
 METAL 83 83 Divalent metal cation 1 (By similarity).
 METAL 85 85 Divalent metal cation 2 (Potential).
 METAL 86 86 Divalent metal cation 2 (Potential).
 METAL 150 150 Divalent metal cation 1 (By similarity).
 METAL 172 172 Divalent metal cation 1 (By similarity).
 METAL 172 172 Divalent metal cation 2 (Potential).  
Keyword
 Complete proteome; Cytoplasm; Endonuclease; Hydrolase; Metal-binding; Nuclease; Reference proteome; RNA-binding. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 569 AA 
Protein Sequence
MIKDFDPSEF VGKTPTKIFA FGGIQEVGKN MYGIEYDDEI IIIDCGIKFA SDDLLGIDGI 60
IPSFEYLIEN QAKVKALFIT HGHEDHIGGV PYLLKQVDVP VIYAPRIAAS LILKKVNEHK 120
DAKLNKVVVY DDFSNFETKH FKIDFYRVNH SIPDAFGVCV QTPNGNIVES GDFRFDFAAG 180
GEMLDVHKVV KIAERNVHVF MCETTNAEIP GFSQSEKLIY RNINKIIKEA RGRVILTTFA 240
SNITRINEII EIAVNNKRKV CLLGKSMDVN VNISRKIGLM DIDSNDIVEV RDIKNYPDRS 300
ILILCTGSQG EDSAALNTMA RGKHNWVSLK STDTIIMSSN PIPGNYAAVE NLLNELSKYG 360
VTIFENSPNM KLHASGHATQ QELQLMLNLV FPRYLIPIHG EYKMMRTIKN IAQECGINGD 420
DVGLLANGQV MYLIDGKLYY SGEVINADPI YIESRNSSPD LARVIKQRQI LSREGMFAVI 480
VVFDKNNNIL GMPTLITRGC FFALDSSPLM TKITHSIKRG LENVIQNKRF NTREQMIKEL 540
KRVCKETVSY FIWKNKSRNP LISTVLSWV 569 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
 GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
 GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
 GO:0090305; P:nucleic acid phosphodiester bond hydrolysis; IEA:GOC. 
Interpro
 IPR001279; Beta-lactamas-like.
 IPR011108; RMMBL.
 IPR004613; RNase_J.
 IPR001587; RNase_J_CS. 
Pfam
 PF00753; Lactamase_B
 PF07521; RMMBL 
SMART
 SM00849; Lactamase_B 
PROSITE
 PS01292; UPF0036 
PRINTS