CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-008042
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Transcription termination/antitermination protein NusA 
Protein Synonyms/Alias
  
Gene Name
 nusA 
Gene Synonyms/Alias
 TTHA0701 
Created Date
 July 27, 2013 
Organism
 Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579) 
NCBI Taxa ID
 300852 
Lysine Modification
Position
Peptide
Type
References
182SEQIPTEKYHPGQRIacetylation[1]
213LVSRAHEKLLEHLLKacetylation[1]
Reference
 [1] Acetylome with structural mapping reveals the significance of lysine acetylation in Thermus thermophilus.
 Okanishi H, Kim K, Masui R, Kuramitsu S.
 J Proteome Res. 2013 Aug 1;. [PMID: 23901841] 
Functional Description
 Participates in both transcription termination and antitermination (By similarity). 
Sequence Annotation
 DOMAIN 145 209 S1 motif.
 DOMAIN 312 379 KH.  
Keyword
 Complete proteome; Cytoplasm; Reference proteome; RNA-binding; Transcription; Transcription antitermination; Transcription regulation; Transcription termination. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 387 AA 
Protein Sequence
MNREFVEAMQ HLALERGVSV EEILEAFKEA LRKAYIKRQK GYKKEEIDQG KGPEVDVYID 60
PNSGRIEMVE VRRVVEKVED PDKEIALAEA LQYDPEVQVG DEMEFPINPE ELSRMAIQDL 120
RQILTQRLKE SERNRIYNEY KDKEGQVLTG VVTRVDNRGN VFVELGRGEA YLPRSEQIPT 180
EKYHPGQRIK VYLKKVDKSA KGPSLLVSRA HEKLLEHLLK QEVPEIAEGI VEIKAIAREP 240
GRRSKVAVTS HNPNVDPIGA CIGHKGQRIQ AVSAELGREK VDIILWSKDP KEFIRNALSP 300
AQVGSIELDP EAKKARVKVT KDQHSLAIGT GGQNVRLASK LTGYDIHFEE AEISDLDEAL 360
RRAAEEEAEA RERKAREEFE KLFRDLG 387 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
 GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
 GO:0006353; P:DNA-dependent transcription, termination; IEA:UniProtKB-KW.
 GO:0031564; P:transcription antitermination; IEA:UniProtKB-KW. 
Interpro
 IPR004087; KH_dom.
 IPR015946; KH_dom-like_a/b.
 IPR025249; KH_dom_NusA-like.
 IPR004088; KH_dom_type_1.
 IPR009019; KH_prok-type.
 IPR012340; NA-bd_OB-fold.
 IPR003029; Rbsml_prot_S1_RNA-bd_dom.
 IPR022967; RNA-binding_domain_S1.
 IPR013735; TF_NusA_N.
 IPR010213; Tscrpt_termination_fac_NusA. 
Pfam
 PF13184; KH_5
 PF08529; NusA_N
 PF00575; S1 
SMART
 SM00322; KH
 SM00316; S1 
PROSITE
 PS50084; KH_TYPE_1
 PS50126; S1 
PRINTS