CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-026523
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 ATP-binding cassette sub-family A member 3 
Protein Synonyms/Alias
 Abca3 protein 
Gene Name
 Abca3 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
503NPRTVVGKEEEGSDPubiquitination[1]
512EEGSDPEKALRNEYFubiquitination[1]
531EDLVAGIKIKHLSKVubiquitination[1]
640LKGLSLQKCPEEVKQubiquitination[1]
646QKCPEEVKQMLHILSubiquitination[1]
711WDLLQQQKSDRTVLLubiquitination[1]
812RFESLFAKLEKKQKEubiquitination[1]
1153RISLAVQKGECFGLLubiquitination[1]
1167LGFNGAGKTTTFKMLubiquitination[1]
1349SPQHLKSKFGSGYSLubiquitination[1]
1365AKVRSEGKQDALEEFubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1449 AA 
Protein Sequence
MAVLRQLTLL LWKNYTLKKR KVLVTVLELF LPLLFSGILI WLRLKIQSEN VPNATVYPDQ 60
SIQELPLFFS FPPPGGTWEL AYVPSHSDAA RTITETVKRE FMIKMRVHGF SSEKDFEDYI 120
RYDNHSSSVL AAVVFEHSFN HSQDPLPLAV KYHLRFSYTR RNYMWTQTGN IFLKETEGWH 180
TTSLFPLFPS PGPREPSSPD GGEPGYIREG FLAMQHAVDK AIMRYHANTS AQQLFQKLMV 240
ITKRFPFPPY ISDPFLIAIQ YQLPLLLMLS FTYTSLTIIR AVVQEKEKKL KEYMRMMGLN 300
SWLHWSAWFL MFFLFFLIVV SFMTLLFCVK VKKDIAVLSN SDPSLVLAFL LCFAISSISF 360
SFMVSTFFSK ANIAAAVGGF LYFFTYTPYF FVAPRYNWMT LSQKLLSCLL SNVAMAMGAQ 420
LIGKFEAKGT GIQWRDLLNP VNVDDNFCFG QVLGMLLLDS ALYGLVTWYV EAVFPGQFGV 480
PQPWHFFLMP SYWCGNPRTV VGKEEEGSDP EKALRNEYFE AEPEDLVAGI KIKHLSKVFQ 540
VGNKDKMGIR DLTLNLYEGQ ITVLLGHNGA GKTTTMSLLT GLFPPTSGHA YIHGYEISQD 600
MAQIRKSLGL CPQHDVLFDN LTVAEHLYFY AQLKGLSLQK CPEEVKQMLH ILSLEDKRDL 660
RSKFLSGGMK RKLSIGIALI AGSKVLMLDE PTSGMDAVSR RAIWDLLQQQ KSDRTVLLTT 720
HFMDEADLLG DRIAILAKGE LQCCGSSLFL KQKYGAGYHM TLVKEPHCNP EGISQLVHHH 780
VPNAMLESHA GAELSFILPK ESTHRFESLF AKLEKKQKEL GIASFGASVT TMEEVFLRGR 840
KGFDIALNLL IAMAFLASTF SILAVSERAV QAKHVQFVSG VHVATFWFSA LLWDLISFLV 900
PSLLLLVVFQ AFNVHAFTRD GHMADLLLLL MLYGWAIIPL MYLMSFFFSA ASTAYTRLTI 960
FNILSGIATF IMVTIMRIPA VKLEELSRTL DHVFLVLPNH CLGMAVSNFY ENYETRRYCT 1020
SSELAAHYCK KYNIQYQESF YAWSTPGVGK FVTSMAASGG IYLTLLFLIE TNLLWRLRTF 1080
ICAFRRRWTL AELQNRTSVL PEDQDVAEER SRILVPSLDS MLDTPLIINE LSKVYDQRAP 1140
LLAVDRISLA VQKGECFGLL GFNGAGKTTT FKMLTGEETI TSGDAFVGGY SISSDIGKVR 1200
QRMGYCPQFD ALLDHMTGRE MLVMYARLRG IPERLINACV ENTLRGLLLE PHANKLVKTY 1260
SGGNKRKLST GIALIGEPAV IFLDEPSTGM DPVARRLLWD TVARARESGK AIVITSHSME 1320
ECEALCTRLA IMVQGQFKCL GSPQHLKSKF GSGYSLQAKV RSEGKQDALE EFKAFVDLTF 1380
PGSILEDEHQ DMVHYHLPGC DLSWAKVFGI LEKAKEKYGV DDYSVSQISL EQVFLSFAHL 1440
QPPTTEDGR 1449 
Gene Ontology
 GO:0097233; C:alveolar lamellar body membrane; IDA:MGI.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0016887; F:ATPase activity; IEA:InterPro.
 GO:0006200; P:ATP catabolic process; IEA:GOC. 
Interpro
 IPR003593; AAA+_ATPase.
 IPR026082; ABC_A.
 IPR003439; ABC_transporter-like.
 IPR017871; ABC_transporter_CS.
 IPR026969; ABCA3.
 IPR027417; P-loop_NTPase. 
Pfam
 PF00005; ABC_tran 
SMART
 SM00382; AAA 
PROSITE
 PS00211; ABC_TRANSPORTER_1
 PS50893; ABC_TRANSPORTER_2 
PRINTS