CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-020619
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Iron-sulfur protein NUBPL 
Protein Synonyms/Alias
 Nucleotide-binding protein-like 
Gene Name
 Nubpl 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
61SRGLPKQKPIEGVREacetylation[1]
Reference
 [1] Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome.
 Hebert AS, Dittenhafer-Reed KE, Yu W, Bailey DJ, Selen ES, Boersma MD, Carson JJ, Tonelli M, Balloon AJ, Higbee AJ, Westphall MS, Pagliarini DJ, Prolla TA, Assadi-Porter F, Roy S, Denu JM, Coon JJ.
 Mol Cell. 2013 Jan 10;49(1):186-99. [PMID: 23201123] 
Functional Description
 Required for the assembly of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I). May deliver of one or more Fe-S clusters to complex I subunits (By similarity). 
Sequence Annotation
 NP_BIND 75 82 ATP (Potential).  
Keyword
 ATP-binding; Complete proteome; Iron; Iron-sulfur; Metal-binding; Mitochondrion; Nucleotide-binding; Reference proteome; Transit peptide. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 319 AA 
Protein Sequence
MGTWRRLLLF GGVSLRGGGA ATVPPRGCRA LGCGRQLLGA ESEALKQRRT QIMSRGLPKQ 60
KPIEGVREVI VVASGKGGVG KSTTAVNLAL ALAANDSSKA VGLLDVDVYG PSIPKMMNLR 120
GNPELSPNNL MRPLLNYGIA CMSMGFLVEE TAPLVWRGLM VMSAIEKLLR QVDWGQLDYL 180
VVDMPPGTGD VQLSVSQNIP ISGAVIVSTP QDIALMDAHK GAEMFRKVNV PVLGLVQNMS 240
VFQCPKCKHK THIFGADGAR KLAQTLDLDV LGDVPLHLSI REASDMGQPV VFSQPGSDEA 300
KAYLHIASEV VRRLKSSPE 319 
Gene Ontology
 GO:0005739; C:mitochondrion; IDA:MGI.
 GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:Compara.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
 GO:0032981; P:mitochondrial respiratory chain complex I assembly; IEA:Compara.
 GO:0070584; P:mitochondrion morphogenesis; IEA:Compara. 
Interpro
 IPR025669; AAA_dom.
 IPR019591; ATPase-like_ParA/MinD.
 IPR000808; Mrp_CS.
 IPR027417; P-loop_NTPase. 
Pfam
 PF13614; AAA_31
 PF10609; ParA 
SMART
  
PROSITE
 PS01215; MRP 
PRINTS