UniProt Accession

 MIMIT_HUMAN; Q8N183; A8K5I1 

Genbank Protein ID

 AB183433; AK291296; CH471123; BC001753; BC033965 

Genbank Nucleotide ID

 BAD91205.1; BAF83985.1; EAW55008.1; AAH01753.2; AAH33965.1 

Protein Name

 Mimitin, mitochondrial 

Protein Synonyms/Alias

 B17.2-like; B17.2L; Myc-induced mitochondrial protein; MMTN; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2; NDUFA12-like protein 

Gene Name

 NDUFAF2 

Gene Synonyms/Alias

 NDUFA12L 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
31	GTDQFGNKYYYIPQY	ubiquitination	[1, 2]
39	YYYIPQYKNWRGQTI	ubiquitination	[1, 2, 3, 4]

Reference

 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789]
 [3] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965]
 [4] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 

Functional Description

 Acts as a molecular chaperone for mitochondrial complex I assembly. 

Sequence Annotation

  

Keyword

 Chaperone; Complete proteome; Mitochondrion; Reference proteome; Transit peptide. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 169 AA 

Protein Sequence

Gene Ontology

 GO:0016020; C:membrane; IEA:InterPro.
 GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
 GO:0009055; F:electron carrier activity; IEA:InterPro.
 GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IEA:InterPro. 

Interpro

 IPR007763; NADH_UbQ_OxRdtase_17.2kDa_su. 

Pfam

 PF05071; NDUFA12 

SMART

  

PROSITE

  

PRINTS