CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-034297
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 E3 ubiquitin-protein ligase synoviolin 
Protein Synonyms/Alias
  
Gene Name
 Syvn1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
257LAMRQFKKAVTDAIMubiquitination[1]
601LRRRRLQKLESPVAHubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Metal-binding; Reference proteome; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 608 AA 
Protein Sequence
MFRTAVMMAA SLALTGAVVA HAYYLKHQFY PTVVYLTKSS PSMAVLYIQA FVLVFLLGKV 60
MGKVFFGQLR AAEMEHLLER SWYAVTETCL AFTVFRDDFS PRFVALFTLL LFLKCFHWLA 120
EDRVDFMERS PNISWLFHCR IVSLMFLLGI LDFLFVSHAY HSILTRGASV QLVFGFEYAI 180
LMTMVLTIFI KYVLHSVDLQ SENPWDNKAV YMLYTELFTG FIKVLLYMAF MTIMIKVHTF 240
PLFAIRPMYL AMRQFKKAVT DAIMSRRAIR NMNTLYPDAT PEELQAMDNV CIICREEMVT 300
GAKRLPCNHI FHTSCLRSWF QRQQTCPTCR MDVLRASLPA QSPPPPEPAD QGPPPAPHPQ 360
PLLPQPPNFP QGLLPPFPPG MFPLWPPMGP FPPVPPPPSS GEAAAPPPTS TAVSRPSGAA 420
TTTAAGTSTS APAPGSVPGP EAGPAPGFPF PPPWMGMPLP PPFAFPPMPV PPAGFAGLTP 480
EELRALEGHE RQHLEARLQS LRNIHTLLDA AMLQINQYLT VLASLGPPRP ATSVNPTEET 540
ASTVVSAAPS TSAPSSEAPT PSPGASPPIP EAEKPPVGIV EELPEDGEPD AAELRRRRLQ 600
KLESPVAH 608 
Gene Ontology
 GO:0005783; C:endoplasmic reticulum; ISO:MGI.
 GO:0000151; C:ubiquitin ligase complex; ISO:MGI.
 GO:0004842; F:ubiquitin-protein ligase activity; ISO:MGI.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0001701; P:in utero embryonic development; IMP:MGI.
 GO:0043066; P:negative regulation of apoptotic process; IMP:MGI.
 GO:0006986; P:response to unfolded protein; ISO:MGI. 
Interpro
 IPR001841; Znf_RING.
 IPR013083; Znf_RING/FYVE/PHD. 
Pfam
 PF13639; zf-RING_2 
SMART
 SM00184; RING 
PROSITE
 PS50089; ZF_RING_2 
PRINTS