CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-035116
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein Sox8 
Protein Synonyms/Alias
 SRY-box containing gene 8 (Predicted), isoform CRA_b 
Gene Name
 Sox8 
Gene Synonyms/Alias
 Sox8_predicted; rCG_33507 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
135ELSKTLGKLWRLLSEacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 463 AA 
Protein Sequence
MLDMSEARAQ PPCSPSGTAS SMSHVEDSDS DAPPSPAGSE GLGRAGGGGR GDTAEAADER 60
FPACIRDAVS QVLKGYDWSL VPMPVRGGGG GTLKAKPHVK RPMNAFMVWA QAARRKLADQ 120
YPHLHNAELS KTLGKLWRLL SESEKRPFVE EAERLRVQHK KDHPDYKYQP RRRKSVKTGR 180
SDSDSGTELG HHPGGPMYKT DTVLGDAHRH SDHTGQTHGP PTPPTTPKTD LHQASNGSKQ 240
ELRLEGRRLV DSGRQNIDFS NVDISELSSE VISNMDTFDV HEFDQYLPLN GHSALATEPS 300
QATASGSYGG ASYSHSGATG IGASPVWAHK GAPSASASPT EAGPLRPHIK TEQLSPSHYN 360
DQSHGSPGRA DYGSYSAQAS VTTAASATAA SSFASAQCDY TDLQASNYYS PYPGYPPSLY 420
QYPYFHSSRR PYASSLLNGL SMPPAHSPSS NWDQPVYTTL TRP 463 
Gene Ontology
 GO:0005737; C:cytoplasm; ISS:UniProtKB.
 GO:0005634; C:nucleus; IEA:Compara.
 GO:0000979; F:RNA polymerase II core promoter sequence-specific DNA binding; ISS:UniProtKB.
 GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:Compara.
 GO:0060612; P:adipose tissue development; ISS:UniProtKB.
 GO:0060018; P:astrocyte fate commitment; IEA:Compara.
 GO:0048469; P:cell maturation; IEA:Compara.
 GO:0048484; P:enteric nervous system development; ISS:UniProtKB.
 GO:0045444; P:fat cell differentiation; ISS:UniProtKB.
 GO:0001701; P:in utero embryonic development; ISS:UniProtKB.
 GO:0072289; P:metanephric nephron tubule formation; ISS:UniProtKB.
 GO:0061138; P:morphogenesis of a branching epithelium; ISS:UniProtKB.
 GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.
 GO:0045662; P:negative regulation of myoblast differentiation; ISS:UniProtKB.
 GO:0046533; P:negative regulation of photoreceptor cell differentiation; IEA:Compara.
 GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.
 GO:0001755; P:neural crest cell migration; ISS:UniProtKB.
 GO:0048709; P:oligodendrocyte differentiation; ISS:UniProtKB.
 GO:0001649; P:osteoblast differentiation; ISS:UniProtKB.
 GO:0007422; P:peripheral nervous system development; ISS:UniProtKB.
 GO:0090190; P:positive regulation of branching involved in ureteric bud morphogenesis; ISS:UniProtKB.
 GO:0014015; P:positive regulation of gliogenesis; ISS:UniProtKB.
 GO:0033690; P:positive regulation of osteoblast proliferation; ISS:UniProtKB.
 GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Compara.
 GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.
 GO:0010817; P:regulation of hormone levels; ISS:UniProtKB.
 GO:0072034; P:renal vesicle induction; ISS:UniProtKB.
 GO:0060221; P:retinal rod cell differentiation; ISS:UniProtKB.
 GO:0060009; P:Sertoli cell development; ISS:UniProtKB.
 GO:0007165; P:signal transduction; ISS:UniProtKB.
 GO:0007283; P:spermatogenesis; ISS:UniProtKB.
 GO:0072197; P:ureter morphogenesis; ISS:UniProtKB. 
Interpro
 IPR009071; HMG_box_dom.
 IPR022151; Sox_N. 
Pfam
 PF00505; HMG_box
 PF12444; Sox_N 
SMART
 SM00398; HMG 
PROSITE
 PS50118; HMG_BOX_2 
PRINTS