CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-044669
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Ataxin-1 
Protein Synonyms/Alias
  
Gene Name
 Atxn1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
693DPASVLLKQAKTDSLubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 799 AA 
Protein Sequence
MKSNQERSNE CLPPKKREIP ATSRPSEEKA TALPSDNHCV EGVAWLPSTP GIRGHGGGRH 60
GSAGTSGEHG LQGMGLHKAL SAGLDYSPPS APRSVPTANT LPTVYPPPQS GTPVSPVQYA 120
HLSHTFQFIG SSQYSGPYAG FIPSQLISPS GNPVTSAVAS AAGATTPSQR SQLEAYSTLL 180
ANMGSLSQAP GHKVEPPPQQ HLSRAAGLVN PGSPPPPTQQ NQYIHISSSP QSSGRATSPP 240
PIPVHLHPHQ TMIPHTLTLG PSSQVVVQYS DAGGHFVPRE STKKAESSRL QQAMQAKEVL 300
NGEMEKSRRY GASSSVELSL GKASSKSVPH PYESRHVVVH PSPADYSSRD TSGVRGSVMV 360
LPNSSTPSAD LEAQQTTHRE ASPSTLNDKS GLHLGKPGHR SYALSPHTVI QTTHSASEPL 420
PVGLPATAFY AGTQPPVIGY LSGQQQAITY AGGLPQHLVI PGNQPLLIPV GSPDMDTPGA 480
ASAIVTSSPQ FAAVPHTFVT TALPKSENFN PEALVTQAAY PAMVQAQIHL PVVQSVASPT 540
TASPTLPPYF MKGSIIQLAN GELKKVEDLK TEDFIQSAEI SNDLKIDSST VERIEESHSP 600
GVAVIQFAVG EHRAQVTLTR VIQVSVEVLV EYPFFVFGQG WSSCCPERTS QLFDLPCSKL 660
SVGDVCISLT LKNLKNGSVK KGQPVDPASV LLKQAKTDSL AGSRHRYAEQ ENGINQGSAQ 720
VLSENGELKF PEKIGLPAAP FLSKIEPSKP TATRKRRWSA PETRKLEKSE DEPPLTLPKP 780
SLIPQEVKIC IEGRSNVGK 799 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:Compara.
 GO:0042405; C:nuclear inclusion body; IDA:MGI.
 GO:0016363; C:nuclear matrix; IEA:Compara.
 GO:0042272; C:nuclear RNA export factor complex; IEA:Compara.
 GO:0034046; F:poly(G) RNA binding; IEA:Compara.
 GO:0008266; F:poly(U) RNA binding; IEA:Compara.
 GO:0003723; F:RNA binding; IDA:MGI.
 GO:0008344; P:adult locomotory behavior; IMP:MGI.
 GO:0043569; P:negative regulation of insulin-like growth factor receptor signaling pathway; IMP:MGI.
 GO:0042326; P:negative regulation of phosphorylation; IMP:MGI.
 GO:0045892; P:negative regulation of transcription, DNA-dependent; IEA:Compara.
 GO:0051168; P:nuclear export; IEA:Compara.
 GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:MGI.
 GO:0060079; P:regulation of excitatory postsynaptic membrane potential; IMP:MGI.
 GO:0008542; P:visual learning; IMP:MGI. 
Interpro
 IPR013723; Ataxin-1_HBP1.
 IPR020997; Capicua_tscrpt_rep_mod. 
Pfam
 PF12547; ATXN-1_C
 PF08517; AXH 
SMART
  
PROSITE
 PS51148; AXH 
PRINTS