CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-025131
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Putative uncharacterized protein 
Protein Synonyms/Alias
  
Gene Name
 Bcar1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
697GNIMRQGKGQLELQQubiquitination[1]
706QLELQQLKQFERLEQubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 SH3 domain. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 874 AA 
Protein Sequence
MTVPNVLAKA LYDNVAESPD ELSFRKGDIM TVLERDTQGL DGWWLCSLHG RQGIVPGNRL 60
KILVGMYDKK PVGPGPGPPA TPPQPQPSLP QGVHAPVPPA SQYSPMLPTA YQPQSDNVYL 120
VPTPSKTQQG LYQAPGPNPQ FQSPPAKQTS TFSKQTPHHS FPSPATDLYQ VPPGPGSPAQ 180
DIYQVPPSAG IGHDIYQVPP SLDTRGWEGT KPPAKVVVPT RVGQGYVYEA AQTEQDEYDT 240
PRHLLAPGPQ DIYDVPPVRG LLPNQYGQEV YDTPPMAVKG PNGRDPLLDV YDVPPSVEKG 300
LLSSSHHSVY DVPPSVSKDV PDGPLLREET YDVPPAFAKP KPFDPTRHPL ILAAPPPDSP 360
AAEDVYDVPP PAPDLYDVPP GLRRPGPGTL YDVPRERVLP PEVADGSVVD DGVYAVPPPA 420
EREAPTDGKR LSASSTGSTR SSQSASSLEV VVPGREPLEL EVAVESLARL QQGVSTTVAH 480
LLDLVGSASG PGGWRGTSEP QEPPAQDLKA AVAAVHGAVH ELLEFARGAV SNATHTSDRT 540
LHAKLSRQLQ KMEDVYQTLV VHGQVLDSGR GSPGFTPEDL DRLVACSRAV PEDAKQLASF 600
LHGNASLLFR RTKAPGPGPE GSSSLHPNPT DKASSIQSRP LPSPPKFTSQ DSPDGQYENS 660
EGGWMEDYDY VHLQGKEEFE KTQKELLERG NIMRQGKGQL ELQQLKQFER LEQEVSRPID 720
HDLANWTPAQ PLVPGQTGGL GPSDRQLLLF YLEQCEANLT TLTDAVDAFF TAVATNQPPK 780
IFVAHSKFVI LSAHKLVFIG DTLSRQAKAA DVRSQVTHYS NLLCDLLRGI VATTKAAALQ 840
YPSPSAAQDM VDRVKELGHS TQQFRRVLGQ LAAA 874 
Gene Ontology
 GO:0005737; C:cytoplasm; ISS:UniProtKB.
 GO:0005925; C:focal adhesion; ISS:UniProtKB.
 GO:0030027; C:lamellipodium; IDA:MGI.
 GO:0001726; C:ruffle; ISS:UniProtKB.
 GO:0007015; P:actin filament organization; ISS:UniProtKB.
 GO:0050853; P:B cell receptor signaling pathway; ISS:UniProtKB.
 GO:0016477; P:cell migration; ISS:UniProtKB.
 GO:0007173; P:epidermal growth factor receptor signaling pathway; ISS:UniProtKB.
 GO:0007186; P:G-protein coupled receptor signaling pathway; ISS:UniProtKB.
 GO:0008286; P:insulin receptor signaling pathway; ISS:UniProtKB.
 GO:0007229; P:integrin-mediated signaling pathway; ISS:UniProtKB.
 GO:0048011; P:neurotrophin TRK receptor signaling pathway; ISS:UniProtKB.
 GO:0048008; P:platelet-derived growth factor receptor signaling pathway; ISS:UniProtKB.
 GO:0030335; P:positive regulation of cell migration; ISS:UniProtKB. 
Interpro
 IPR021901; CAS_DUF3513.
 IPR014928; Serine_rich.
 IPR001452; SH3_domain.
 IPR013315; Spectrin_alpha_SH3. 
Pfam
 PF12026; DUF3513
 PF08824; Serine_rich
 PF00018; SH3_1 
SMART
 SM00326; SH3 
PROSITE
 PS50002; SH3 
PRINTS
 PR00452; SH3DOMAIN.
 PR01887; SPECTRNALPHA.