CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-043695
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Tropomyosin 1 (Alpha), isoform CRA_m 
Protein Synonyms/Alias
 Tropomyosin alpha-1 chain 
Gene Name
 TPM1 
Gene Synonyms/Alias
 hCG_33495 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
215RSVTKLEKSIDDLEEacetylation[1]
223SIDDLEEKVAHAKEEacetylation[1]
Reference
 [1] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
 Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C.
 PLoS One. 2012;7(12):e50545. [PMID: 23236377] 
Functional Description
  
Sequence Annotation
  
Keyword
 Coiled coil; Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 248 AA 
Protein Sequence
MAGSSSLEAV RRKIRSLQEQ ADAAEERAGT LQRELDHERK LRETAEADVA SLNRRIQLVE 60
EELDRAQERL ATALQKLEEA EKAADESERG MKVIESRAQK DEEKMEIQEI QLKEAKHIAE 120
DADRKYEEVA RKLVIIESDL ERAEERAELS EGQVRQLEEQ LRIMDQTLKA LMAAEDKYSQ 180
KEDRYEEEIK VLSDKLKEAE TRAEFAERSV TKLEKSIDDL EEKVAHAKEE NLSMHQMLDQ 240
TLLELNNM 248 
Gene Ontology
  
Interpro
 IPR000533; Tropomyosin. 
Pfam
 PF00261; Tropomyosin 
SMART
  
PROSITE
 PS00326; TROPOMYOSIN 
PRINTS
 PR00194; TROPOMYOSIN.