CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-007601
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Alkylphosphocholine resistance protein LEM3 
Protein Synonyms/Alias
 Brefeldin-A sensitivity protein 3; Ro-sensitive 3 
Gene Name
 LEM3 
Gene Synonyms/Alias
 BRE3; ROS3; YNL323W; N0333 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
18EVFRRKDKGAIVSGDubiquitination[1]
154DESDDFTKQRGTCQIubiquitination[1]
Reference
 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, VillĂ©n J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301
Functional Description
 Involved in the asymmetrical organization of phosphatidylethanolamine in the plasma membrane. 
Sequence Annotation
 MOD_RES 36 36 Phosphoserine.
 CARBOHYD 113 113 N-linked (GlcNAc...) (Potential).
 CARBOHYD 240 240 N-linked (GlcNAc...) (Potential).
 CARBOHYD 256 256 N-linked (GlcNAc...) (Potential).
 CARBOHYD 279 279 N-linked (GlcNAc...) (Potential).
 CARBOHYD 298 298 N-linked (GlcNAc...) (Potential).
 CARBOHYD 332 332 N-linked (GlcNAc...) (Potential).  
Keyword
 Cell membrane; Complete proteome; Glycoprotein; Membrane; Phosphoprotein; Reference proteome; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 414 AA 
Protein Sequence
MVNFDLGQVG EVFRRKDKGA IVSGDNPEEE EDVDASEFEE DEVKPVRTKN RRPKEDAFTQ 60
QRLAAINPVL TPRTVLPLYL LIAVVFVIVG GCILAQNSKV DEVTIYYQDC MTNATSSWSD 120
IPSEHWQFVF HKYKTYNTAP QWRFVDDESD DFTKQRGTCQ IRFTTPSDMK NNVYLNYVLE 180
KFAANHRRYV LSFSEDQIRG EDASYETVHD ATGINCKPLS KNADGKIYYP CGLIANSMFN 240
DTFPLQLTNV GDTSNNYSLT NKGINWESDK KRYKKTKYNY TQIAPPPYWE KMYPDGYNET 300
NIPDIQDWEE FQNWMRPGAF DKITKLIRIN KNDTLPAGEY QLDIGLHWPV LEFNGKKGIY 360
LTHGSHLGGR NPFLGIVYLI GGCICAAMAL ILLTFWLFGG RKIADASSLS WNMK 414 
Gene Ontology
 GO:0005783; C:endoplasmic reticulum; IDA:SGD.
 GO:0016021; C:integral to membrane; ISS:SGD.
 GO:0005886; C:plasma membrane; IDA:SGD.
 GO:0004012; F:phospholipid-translocating ATPase activity; IMP:SGD.
 GO:0007166; P:cell surface receptor signaling pathway; IMP:SGD.
 GO:0045332; P:phospholipid translocation; IMP:SGD. 
Interpro
 IPR005045; DUF284_TM_euk. 
Pfam
 PF03381; CDC50 
SMART
  
PROSITE
  
PRINTS