| Tag | Content |
|---|
| CPLM ID | CPLM-022602 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Type II inositol 3,4-bisphosphate 4-phosphatase |
Protein Synonyms/Alias | Inositol polyphosphate 4-phosphatase type II |
Gene Name | Inpp4b |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Rattus norvegicus (Rat) |
NCBI Taxa ID | 10116 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 111 | IYEETRIKLTVYDVK | acetylation | [1] |
|
Reference | [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns. Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV. Cell Rep. 2012 Aug 30;2(2):419-31. [ PMID: 22902405] |
Functional Description | Catalyzes the hydrolysis of the 4-position phosphate of phosphatidylinositol 3,4-bisphosphate, inositol 1,3,4- trisphosphate and inositol 1,4-bisphosphate. |
Sequence Annotation | DOMAIN 40 164 C2.
MOD_RES 487 487 Phosphoserine (By similarity). |
Keyword | Alternative splicing; Complete proteome; Hydrolase; Phosphoprotein; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 928 AA |
Protein Sequence | MEIKEEGTSE EGQHFLPAAQ ANDPEDIQFT SIQKSPNEPQ LEFILACKDL VAPVSDRKLN 60
TVVQVSVIHP VEQTLTRYSS TEIVEGTKDP LFLTGVTFPS DYPIYEETRI KLTVYDVKDK 120
PHDTIRTSVL PEHKDPPPEV ARSFLGCASF KVGELLKSKE QLLSLSLRTS DGGKVVGTIE 180
VSLVKMGEIE DGDTDHITTD VQGQKCALVY DSTAPESLSG KENLPFMNAV LRNPVCKLYR 240
FPTSDNKWMR IREQMSESIL SFHIPKELIS LHIKEDLCRN QELKELGDLS PHWDNLRNNV 300
LSHCDQMVTM YQDILTELSK ETGSSFKSSS SKGEKTLEFV PINLHLQRMQ VHSPHLKDAL 360
YDVITVGAPA AHFQGFKNGG LRKLLHRFET ERRNTGYQFI YYSPENTAKA KEVLSSINQL 420
QPLVATHADL LLTSASQHSP DSLRSSLKLL SEKTELFVHA FKDQLVRSAL LALYTARPGG 480
ILRKPPSPKV STEEKSSQHD SPQQLRRQDS IPHHSDYDEE EWDRVWANVG KSLNCIIAKV 540
DKLIERDSRN DKSTGGDSSK DGDADPNLED SLTSHPREDW YEQLHPLILT LKECMAEVVN 600
RAKQSLTFVL LQELAYSLPQ CLMLTLRRDI VFSQALAGLV CGFIIKLHTS LHDPGFLQQL 660
HTVGLIVQYE GLLSTYSDEI GMLEDMAVGI SDLRKVAFKI TEATSNDVLP VLTGRREHYV 720
VEVKLPATVF ESLPLQIKEG QLLHVYPVLF NVGINEQQTL AERFGDVSLQ ESINQENFEL 780
VQEYYSIFME KMPPDYISHF QEQNDLKGLL DNLHQNIQAK KRKNVEIMWL AATICRKLNG 840
IRFTCCKSAK DRTSMSVTLE QCSILRDEHQ LHKDFFIRAL DCMRREGCRI ENVLKNIKCR 900
RYAFNMLQLM AFPKCYRPPE GTYGKADT 928 |
Gene Ontology | GO:0016316; F:phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity; IDA:RGD. GO:0034597; F:phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity; IEA:EC. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |