CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-039982
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Splicing factor, suppressor of white-apricot homolog 
Protein Synonyms/Alias
  
Gene Name
 SFSWAP 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
108NRLEELMKPLKVVDPacetylation[1]
266YVARNGLKFETSVRAubiquitination[2]
Reference
 [1] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
 Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C.
 PLoS One. 2012;7(12):e50545. [PMID: 23236377]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 546 AA 
Protein Sequence
MHAIIERTAS FVCRQGAQFE IMLKAKQARN SQFDFLRFDH YLNPYYKFIQ KAMKEGRYTV 60
LAENKSDEKK KSGVSSDNED DDDEEDGNYL HPSLFASKKC NRLEELMKPL KVVDPDHPLA 120
ALVRKAQADS STPTPHNADG APVQPSQVEY TADSTVAAMY YSYYMLPDGT YCLAPPPPGI 180
DVTTYYSTLP AGVTVSNSPG VTTTAPPPPG TTPLPPPTTA ETSSGATSTT TTTSALAPVA 240
AIIPPPPDVQ PVIDKLAEYV ARNGLKFETS VRAKNDQRFE FLQPWHQYNA YYEFKKQFFL 300
QKEGGDSMQA VSAPEEAPTD SAPEKPSDAG EDGAPEDAAE VGARAGSGGK KEASSSKTVP 360
DGKLVKASFA PISFAIKAKE NDLLPLEKNR VKLDDDSDDD EESKEGQESS SSAANTNPAV 420
APPCVVVEEK KPQLTQEELE AKQAKQKLED RLAAAAREKL AQASKESKEK QLQAERKRKA 480
ALFLQTLKNP LPEAEAGKIE ESPFSVEESS TTPCPLLTGG RPLPTLEVKP PDRPSSKSKD 540
PPREEE 546 
Gene Ontology
 GO:0003723; F:RNA binding; IEA:InterPro.
 GO:0048025; P:negative regulation of mRNA splicing, via spliceosome; IEA:Compara.
 GO:0006396; P:RNA processing; IEA:InterPro. 
Interpro
 IPR000061; Surp. 
Pfam
 PF01805; Surp 
SMART
 SM00648; SWAP 
PROSITE
 PS50128; SURP 
PRINTS