CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-027822
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Cytochrome c oxidase subunit 5B, mitochondrial 
Protein Synonyms/Alias
 Cytochrome c oxidase, subunit Vb; MCG17741, isoform CRA_d; MCG23026; Protein Gm11273 
Gene Name
 Cox5b 
Gene Synonyms/Alias
 Gm11273; mCG_17741; mCG_23026 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
57EIMIAAQKGLDPYNMubiquitination[1]
68PYNMLPPKAASGTKEacetylation[2]
74PKAASGTKEDPNLVPacetylation[2]
74PKAASGTKEDPNLVPubiquitination[1]
86LVPSISNKRIVGCICacetylation[2]
86LVPSISNKRIVGCICubiquitination[1]
121PNCGTHYKLVPHQMAacetylation[2]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome.
 Hebert AS, Dittenhafer-Reed KE, Yu W, Bailey DJ, Selen ES, Boersma MD, Carson JJ, Tonelli M, Balloon AJ, Higbee AJ, Westphall MS, Pagliarini DJ, Prolla TA, Assadi-Porter F, Roy S, Denu JM, Coon JJ.
 Mol Cell. 2013 Jan 10;49(1):186-99. [PMID: 23201123
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 129 AA 
Protein Sequence
MASRLLRGVG ALAAQALRAH GPRGAAVTRS MASGGGVPTD EEQATGLERE IMIAAQKGLD 60
PYNMLPPKAA SGTKEDPNLV PSISNKRIVG CICEEDNCTV IWFWLHKGES QRCPNCGTHY 120
KLVPHQMAH 129 
Gene Ontology
 GO:0005740; C:mitochondrial envelope; IEA:InterPro.
 GO:0004129; F:cytochrome-c oxidase activity; IEA:InterPro. 
Interpro
 IPR002124; Cyt_c_oxidase_su5b.
 IPR020893; Cyt_c_oxidase_su5b_Zn_BS. 
Pfam
 PF01215; COX5B 
SMART
  
PROSITE
 PS00848; COX5B_1
 PS51359; COX5B_2 
PRINTS