CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-031454
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Integrin alpha-L 
Protein Synonyms/Alias
 cDNA FLJ57691, highly similar to Integrin alpha-L 
Gene Name
 ITGAL 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
184GPKIHQVKHMYQVRIubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 Cell adhesion; Complete proteome; Integrin; Membrane; Receptor; Reference proteome; Transmembrane. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 404 AA 
Protein Sequence
MKDSCITVMA MALLSGFFFF APASSYNLDV RGARSFSPPR AGRHFGYRVL QIKSLIPQFQ 60
GRLVANLTYT LQLDGHRTRR RGLFPGGRHE LRRNIAVTTS MSCTDFSFHF PMMFNTLVNS 120
SWGDSVELHA NVTCNNEDSD LLEDNSATTI IPILYPINIL IQDQEDSTLY VSFTPKGPKI 180
HQVKHMYQVR IQPSIHDHNI PTLEAVVGVP QPPSEGPITH QWSVQMEPPV PCHYEDLERL 240
PDAAEPCLPG ALFRCPVVFR QEILVQVIGT LELVGEIEAS SMFSLCSSLS ISFNSSKHFH 300
LYGSNASLAQ VVMKVDVVYE KQMLYLYVLS GIGGLLLLLL IFIVLYKVGF FKRNLKEKME 360
AGRGVPNGIP AEDSEQLASG QEAGDPGCLK PLHEKDSESG GGKD 404 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
 GO:0007229; P:integrin-mediated signaling pathway; IEA:UniProtKB-KW. 
Interpro
 IPR013649; Integrin_alpha-2.
 IPR018184; Integrin_alpha_C_CS. 
Pfam
 PF00357; Integrin_alpha
 PF08441; Integrin_alpha2 
SMART
  
PROSITE
 PS00242; INTEGRIN_ALPHA 
PRINTS