UniProt Accession

 IF3_SALTY; P33321 

Genbank Protein ID

 L11254; AE006468 

Genbank Nucleotide ID

 AAC36814.1; AAL20259.1 

Protein Name

 Translation initiation factor IF-3 

Protein Synonyms/Alias

  

Gene Name

 infC 

Gene Synonyms/Alias

 STM1334 

Created Date

 July 27, 2013 

Organism

 Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) 

NCBI Taxa ID

 99287 

Lysine Modification

Position	Peptide	Type	References
123	RFLEEGDKAKITLRF	acetylation	[1]
125	LEEGDKAKITLRFRG	acetylation	[1]

Reference

 [1] Regulation of cellular metabolism by protein lysine acetylation.
 Zhao S, Xu W, Jiang W, Yu W, Lin Y, Zhang T, Yao J, Zhou L, Zeng Y, Li H, Li Y, Shi J, An W, Hancock SM, He F, Qin L, Chin J, Yang P, Chen X, Lei Q, Xiong Y, Guan KL.
 Science. 2010 Feb 19;327(5968):1000-4. [PMID: 20167786] 

Functional Description

 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity). 

Sequence Annotation

  

Keyword

 Complete proteome; Cytoplasm; Initiation factor; Protein biosynthesis; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 180 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0003743; F:translation initiation factor activity; IEA:HAMAP. 

Interpro

 IPR019813; Translation_initiation_fac3_CS.
 IPR001288; Translation_initiation_fac_3.
 IPR019815; Translation_initiation_fac_3_C.
 IPR019814; Translation_initiation_fac_3_N. 

Pfam

 PF00707; IF3_C
 PF05198; IF3_N 

SMART

  

PROSITE

 PS00938; IF3 

PRINTS