UniProt Accession

 1A31_HUMAN; P16189; O62924; O98009; O98137; Q8MHM1; Q9TPQ3; Q9TQ24; Q9UQU6; Q9UQU7 

Genbank Protein ID

 M30578; M84375; L78918; AF148863; AH006155; AH007022; AJ239045; AJ239046; AB032597; AH007200; AJ506789; AJ506790 

Genbank Nucleotide ID

 AAA59613.1; AAA59599.1; AAB05976.1; AAD39981.1; AAC18859.1; AAC79721.1; CAB43109.1; CAB43110.1; BAA84645.1; AAD02207.1; CAD44950.1; CAD44950.1 

Protein Name

 HLA class I histocompatibility antigen, A-31 alpha chain 

Protein Synonyms/Alias

 MHC class I antigen A*31 

Gene Name

 HLA-A 

Gene Synonyms/Alias

 HLAA 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
92	DQETRNVKAHSQIDR	ubiquitination	[1]

Reference

 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 

Functional Description

 Involved in the presentation of foreign antigens to the immune system. 

Sequence Annotation

 DOMAIN 209 295 Ig-like C1-type.
 REGION 25 114 Alpha-1.
 REGION 115 206 Alpha-2.
 REGION 207 298 Alpha-3.
 REGION 299 308 Connecting peptide.
 MOD_RES 356 356 Phosphoserine (By similarity).
 CARBOHYD 110 110 N-linked (GlcNAc...) (By similarity).
 DISULFID 125 188 By similarity.
 DISULFID 227 283 By similarity.  

Keyword

 Complete proteome; Disulfide bond; Glycoprotein; Host-virus interaction; Immunity; Membrane; MHC I; Phosphoprotein; Polymorphism; Reference proteome; Signal; Transmembrane; Transmembrane helix; Ubl conjugation. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 365 AA 

Protein Sequence

Gene Ontology

 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0042612; C:MHC class I protein complex; IEA:UniProtKB-KW.
 GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; IEA:UniProtKB-KW.
 GO:0006955; P:immune response; IEA:InterPro.
 GO:0019048; P:virus-host interaction; IEA:UniProtKB-KW. 

Interpro

 IPR007110; Ig-like_dom.
 IPR013783; Ig-like_fold.
 IPR003006; Ig/MHC_CS.
 IPR003597; Ig_C1-set.
 IPR011161; MHC_I-like_Ag-recog.
 IPR011162; MHC_I/II-like_Ag-recog.
 IPR001039; MHC_I_a_a1/a2.
 IPR010579; MHC_I_a_C. 

Pfam

 PF07654; C1-set
 PF00129; MHC_I
 PF06623; MHC_I_C 

SMART

 SM00407; IGc1 

PROSITE

 PS50835; IG_LIKE
 PS00290; IG_MHC 

PRINTS

 PR01638; MHCCLASSI.