| Tag | Content |
|---|
| CPLM ID | CPLM-013777 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Mitochondrial dynamic protein MID49 |
Protein Synonyms/Alias | Mitochondrial dynamic protein of 49 kDa homolog; Smith-Magenis syndrome chromosomal region candidate gene 7 protein homolog |
Gene Name | Smcr7 |
Gene Synonyms/Alias | Gm11; Mid49 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 64 | PPDEDDTKGDSWKEL | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Mitochondrial outer membrane protein which regulates mitochondrial morphology. Mitochondrial morphology is controlled by two opposites processes: fusion and fission. Can directly recruit the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface (By similarity). |
Sequence Annotation | |
Keyword | Complete proteome; Membrane; Mitochondrion; Mitochondrion outer membrane; Reference proteome; Transmembrane; Transmembrane helix. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 454 AA |
Protein Sequence | MAEFSQKQRK QSGSEGLGSV VDFLLANARL VLGVGGAAVL GIATLAVKRL IDRATSPPDE 60
DDTKGDSWKE LSLLRATSPQ KPQPPPAAFS QPLATGSPSP SVPVEPTPIH SPTTPKFSTI 120
APLCLTFQER LLAFERKHVI TPEAHVTLAK QLAGDIALEL QAYLRSKFPE LPFGALVPGG 180
PLYDGLQAGT AEHVRLLAPL ELEPGLWSLV PGVDTVAREP RCWAVRRTQL EFHPRGCSPW 240
DRFLVGGYLS SRVLLELLRK ALSASVNWPA IGSLLGCLIW PDVASEELLL KVQHECLEFT 300
LAVLMVVPGA STDDRLLLAW PLEGLASNLW LQDLYPVETA RLRALDDQDA GTRRRLLLLL 360
CGICRGHPAL VRLGWSHLTQ VVLHLGEEEV AWTEEALGER FLQALEFLVG SLEQASLPCH 420
FNPSVNLLGN FREEEIDDIG YVLYSGLQVP ESLF 454 |
Gene Ontology | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0005741; C:mitochondrial outer membrane; ISS:UniProtKB. GO:0007005; P:mitochondrion organization; ISS:UniProtKB. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |