UniProt Accession

 TUSB_ECOLI; P45530; Q2M708 

Genbank Protein ID

 U18997; U00096; AP009048 

Genbank Nucleotide ID

 AAA58140.1; AAC76368.1; BAE77948.1 

Protein Name

 Protein TusB 

Protein Synonyms/Alias

 tRNA 2-thiouridine synthesizing protein B 

Gene Name

 tusB 

Gene Synonyms/Alias

 yheL; b3343; JW3305 

Created Date

 July 27, 2013 

Organism

 Escherichia coli (strain K12) 

NCBI Taxa ID

 83333 

Lysine Modification

Position	Peptide	Type	References
53	SLRNAPIKVYALNED	acetylation	[1]

Reference

 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618] 

Functional Description

 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. 

Sequence Annotation

  

Keyword

 3D-structure; Complete proteome; Cytoplasm; Reference proteome; tRNA processing. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 95 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0002143; P:tRNA wobble position uridine thiolation; IMP:EcoCyc. 

Interpro

 IPR027396; DsrEFH-like.
 IPR023526; Sulphur_relay_TusB.
 IPR007215; Sulphur_relay_TusB/DsrH. 

Pfam

 PF04077; DsrH 

SMART

  

PROSITE

  

PRINTS