CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-041523
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Dimethylaniline monooxygenase [N-oxide-forming] 
Protein Synonyms/Alias
  
Gene Name
 Fmo4 
Gene Synonyms/Alias
 rCG_46275 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
102ESFPGIHKFKGQILHacetylation[1]
104FPGIHKFKGQILHSQacetylation[1]
289TKKVILYKRVFPPNLacetylation[1]
347LMAEAIKKEELIKRGacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Endoplasmic reticulum; FAD; Flavoprotein; Membrane; Microsome; Monooxygenase; NADP; Oxidoreductase; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 497 AA 
Protein Sequence
MAKKVAVIGA GVSGLSSIKC CLDENLEPTC FERSSDFGGL WKFATTVRSV TKRPDFSETG 60
QWEVVTETEG KQDRAVFDAV MVCTGQFLSP RLPLESFPGI HKFKGQILHS QEYRIPDAFR 120
GKRILVVGLG NTGGDVAVEL SGIAAQVFLS TRTGAWVRSR SSVGGYPLNM MQTRWRNFLA 180
QVLPSRFVSW NQERQMNKIF NHENYGLSIA KGKKPKFIVN DELPTCILCG KITMKTSVKD 240
FTESSIVFED GTIEANIDVV IFTTGYEFSF PFFEEPLKSL CTKKVILYKR VFPPNLERST 300
LAIIGLISLT GSILVGTEFQ ARWATRVFKG LCNIPPSQKL MAEAIKKEEL IKRGVIKDTS 360
QDKLDFISYM DELTQCIGAK PNIPLLFLKD PRLAWEVFFG PCTPYQYRLM GPGRWDGARN 420
AILTQWDRTV KPLKTRTVPK SQEPASLSRY LKTWGAPVLI VSLLLIYKSS LFLELVQSKL 480
QGRFSPSRIL WYIPQNS 497 
Gene Ontology
 GO:0031227; C:intrinsic to endoplasmic reticulum membrane; IEA:InterPro.
 GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
 GO:0004499; F:N,N-dimethylaniline monooxygenase activity; IEA:EC.
 GO:0050661; F:NADP binding; IEA:InterPro. 
Interpro
 IPR012143; DiMe-aniline_mOase.
 IPR000960; Flavin_mOase.
 IPR020946; Flavin_mOase-like.
 IPR002256; Flavin_mOase_4. 
Pfam
 PF00743; FMO-like 
SMART
  
PROSITE
  
PRINTS
 PR00370; FMOXYGENASE.
 PR01124; FMOXYGENASE4.