| Tag | Content |
|---|
| CPLM ID | CPLM-016409 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Leucine-rich repeat-containing protein 8D |
Protein Synonyms/Alias | Leucine-rich repeat-containing protein 5 |
Gene Name | Lrrc8d |
Gene Synonyms/Alias | Lrrc5 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 826 | GQCRMLKKSGLVVED | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | |
Sequence Annotation | REPEAT 515 535 LRR 1.
REPEAT 539 560 LRR 2.
REPEAT 562 583 LRR 3.
REPEAT 590 610 LRR 4.
REPEAT 613 633 LRR 5.
REPEAT 637 658 LRR 6.
REPEAT 660 681 LRR 7.
REPEAT 685 706 LRR 8.
REPEAT 708 729 LRR 9.
REPEAT 731 752 LRR 10.
REPEAT 754 775 LRR 11.
REPEAT 777 798 LRR 12.
REPEAT 800 821 LRR 13.
MOD_RES 242 242 Phosphoserine (By similarity).
MOD_RES 243 243 Phosphoserine (By similarity).
MOD_RES 247 247 Phosphoserine (By similarity).
CARBOHYD 256 256 N-linked (GlcNAc...) (Potential).
CARBOHYD 599 599 N-linked (GlcNAc...) (Potential).
CARBOHYD 606 606 N-linked (GlcNAc...) (Potential).
CARBOHYD 741 741 N-linked (GlcNAc...) (Potential). |
Keyword | Complete proteome; Glycoprotein; Leucine-rich repeat; Membrane; Phosphoprotein; Reference proteome; Repeat; Transmembrane; Transmembrane helix. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 859 AA |
Protein Sequence | MFTLAEVASL NDIQPTYRIL KPWWDVFMDY LAVVMLMVAI FAGTMQLTKD QVVCLPVLPS 60
PANSKAHTPP GNADITTEVP RMETATHQDQ NGQTTTNDVA FGTSAVTPDI PLQATHPHAE 120
STLPNQEAKK EKRDPTGRKT NLDFQQYVFI NQMCYHLALP WYSKYFPYLA LIHTIILMVS 180
SNFWFKYPKT CSKVEHFVSI LGKCFESPWT TKALSETACE DSEENKQRIT GAQTLPKHVS 240
TSSDEGSPSA STPMINKTGF KFSAEKPVIE VPSMTILDKK DGEQAKALFE KVRKFRAHVE 300
DSDLIYKLYV VQTLIKTAKF IFILCYTANF VNAISFEHVC KPKVEHLTGY EVFECTHNMA 360
YMLKKLLISY ISIICVYGFI CLYTLFWLFR IPLKEYSFEK VREESSFSDI PDVKNDFAFL 420
LHMVDQYDQL YSKRFGVFLS EVSENKLREI SLNHEWTFEK LRQHVSRNAQ DKQELHLFML 480
SGVPDAVFDL TDLDVLKLEL IPEAKIPAKI SQMTNLQELH LCHCPAKVEQ TAFSFLRDHL 540
RCLHVKFTDV AEIPAWVYLL KNLRELYLIG NLNSENNKMI GLESLRELRH LKILHVKSNL 600
TKVPSNITDV APHLTKLVIH NDGTKLLVLN SLKKMMNVAE LELQNCELER IPHAIFSLSN 660
LQELDLKSNN IRTIEEIISF QHLKRLTCLK LWHNKIVAIP PSITHVKNLE SLYFSNNKLE 720
SLPTAVFSLQ KLRCLDVSYN NISTIPIEIG LLQNLQHLHI TGNKVDILPK QLFKCVKLRT 780
LNLGQNCIAS LPEKISQLTQ LTQLELKGNC LDRLPAQLGQ CRMLKKSGLV VEDQLFDTLP 840
LEVKEALNQD VNVPFANGI 859 |
Gene Ontology | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |