CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-004661
UniProt Accession
Genbank Protein ID
 X53054 
Genbank Nucleotide ID
Protein Name
 Rano class II histocompatibility antigen, D-1 beta chain 
Protein Synonyms/Alias
 RT1 class II histocompatibility antigen, D-1 beta chain 
Gene Name
 RT1-Db1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
90PSAEYYNKQKEYMEQacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
 Involved in the presentation of foreign antigens to the immune system. 
Sequence Annotation
 DOMAIN 124 228 Ig-like C1-type.
 REGION 27 120 Beta-1.
 REGION 121 215 Beta-2.
 REGION 216 226 Connecting peptide.
 CARBOHYD 46 46 N-linked (GlcNAc...) (Potential).
 DISULFID 42 106 By similarity.
 DISULFID 144 200 By similarity.  
Keyword
 Complete proteome; Disulfide bond; Glycoprotein; Immunity; Membrane; MHC II; Reference proteome; Signal; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 264 AA 
Protein Sequence
MVWLARDSCV AAVILLLTVL SPPVALVRDP TPRFLEQVKG ECHFYNGTQR VRFLARYIYN 60
REEYTRFDSD VGEFRAVTEL GRPSAEYYNK QKEYMEQLRA TVDTACKHDY EISESFLVPR 120
TVEPKVTVYP SKTQPLEHHN LLVCSVSDFY PGSVEVRWFR NGEEEKDGLV STGLIRNGDW 180
TFQLLVMLET VPQGGEVYTC QVEHPSLPSP VRVEWKAQST SAQNKKMSGV GGIVLGLLFL 240
GAGLFVYFRN QKGQSGLQPT GLLN 264 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0042613; C:MHC class II protein complex; IEA:UniProtKB-KW.
 GO:0002504; P:antigen processing and presentation of peptide or polysaccharide antigen via MHC class II; IEA:UniProtKB-KW.
 GO:0006955; P:immune response; IEA:InterPro. 
Interpro
 IPR007110; Ig-like_dom.
 IPR013783; Ig-like_fold.
 IPR003006; Ig/MHC_CS.
 IPR003597; Ig_C1-set.
 IPR011162; MHC_I/II-like_Ag-recog.
 IPR014745; MHC_II_a/b_N.
 IPR000353; MHC_II_b_N. 
Pfam
 PF07654; C1-set
 PF00969; MHC_II_beta 
SMART
 SM00407; IGc1
 SM00921; MHC_II_beta 
PROSITE
 PS50835; IG_LIKE
 PS00290; IG_MHC 
PRINTS