UniProt Accession

 C9J8T0_HUMAN; C9J8T0 

Genbank Protein ID

 AL449210; AL449214; AL449217 

Genbank Nucleotide ID

  

Protein Name

 Selenocysteine-specific elongation factor 

Protein Synonyms/Alias

  

Gene Name

 EEFSEC 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
38	ASTAAFDKQPQSRER	ubiquitination	[1]
155	IDLLPEGKRQAAIDK	ubiquitination	[1]
175	QKTLENTKFRGAPII	ubiquitination	[2]
241	CVTQFDPKLLERGLV	ubiquitination	[2]
363	WALVEFEKPVTCPRL	ubiquitination	[2]

Reference

 [1] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; GTP-binding; Nucleotide-binding; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 436 AA 

Protein Sequence

Gene Ontology

 GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
 GO:0003924; F:GTPase activity; IEA:InterPro.
 GO:0006184; P:GTP catabolic process; IEA:GOC. 

Interpro

 IPR000795; EF_GTP-bd_dom.
 IPR027417; P-loop_NTPase. 

Pfam

 PF00009; GTP_EFTU 

SMART

  

PROSITE

  

PRINTS

 PR00315; ELONGATNFCT.