CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-036555
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Helicase POLQ-like 
Protein Synonyms/Alias
  
Gene Name
 HELQ 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
566GNLCPVLKRTIPFGVubiquitination[1]
635FLKRNQYKQMIGRAGubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1034 AA 
Protein Sequence
MDECGSRIRR RVSLPKRNRP SLGCIFGAPT AAELVPGDEG KEEEEMVAEN RRRKTAGVLP 60
VEVQPLLLSD SPECLVLGGG DTNPDLLRHM PTDRGVGDQP NDSEVDMFGD YDSFTENSFI 120
AQVDDLEQKY MQLPEHKKHA TDFATENLCS ESIKNKLSIT TIGNLTELQT DKHTENQSGY 180
EGVTIEPGAD LLYDVPSSQA IYFENLQNSS NDLGDHSMKE RDWKSSSHNT VNEELPHNCI 240
EQPQQNDESS SKVRTSSDMN RRKSIKDHLK NAMTGNAKAQ TPIFSRSKQL KDTLLSEEIN 300
VAKKTVESSS NDLGPFYSLP SKVRDLYAQF KGIEKLYEWQ HTCLTLNSVQ ERKNLIYSLP 360
TSGGKTLVAE ILMLQELLCC RKDVLMILPY VAIVQEKLHM IGEGSRGATL EMTLAKILYT 420
SKTTQIIGMS ATLNNVEDLQ KFLQAEYYTS QFRPVELKEY LKINDTIYEV DSKAENGMTF 480
SRLLNYKYSD TLKKMDPDHL VALVTEVIPN YSCLVFCPSK KNCENVAEMI CKFLSKEYLK 540
HKEKEKCEVI KNLKNIGNGN LCPVLKRTIP FGVAYHHSGL TSDERKLLEE AYSTGVLCLF 600
TCTSTLAAGV NLPARRVILR APYVAKEFLK RNQYKQMIGR AGRAGIDTIG ESILILQEKD 660
KQQVLELITK PLENCYSHLV QEFTKGIQTL FLSLIGLKIA TNLDDIYHFM NGTFFGVQQK 720
VLLKEKSLWE ITVESLRYLT EKGLLQKDTI YKSEEEVQYN FHITKLGRAS FKGTIDLAYC 780
DILYRDLKKG LEGLVLESLL HLIYLTTPYD LVSQCNPDWM IYFRQFSQLS PAEQNVAAIL 840
GVSESFIGKK ASGQAIGKKV DKNVVNRLYL SFVLYTLLKE TNIWTVSEKF NMPRGYIQNL 900
LTGTASFSSC VLHFCEELEE FWVYRALLVE LTKKLTYCVK AELIPLMEVT GVLEGRAKQL 960
YSAGYKSLMH LANANPEVLV RTIDHLSRRQ AKQIVSSAKM LLHEKAEALQ EEVEELLRLP 1020
SDFPGAVASS TDKA 1034 
Gene Ontology
 GO:0005730; C:nucleolus; IDA:HPA.
 GO:0005524; F:ATP binding; IEA:InterPro.
 GO:0004386; F:helicase activity; IEA:InterPro.
 GO:0003676; F:nucleic acid binding; IEA:InterPro. 
Interpro
 IPR001650; Helicase_C.
 IPR027417; P-loop_NTPase. 
Pfam
 PF00271; Helicase_C 
SMART
 SM00490; HELICc 
PROSITE
 PS51194; HELICASE_CTER 
PRINTS