CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-039174
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein Mll3 
Protein Synonyms/Alias
  
Gene Name
 LOC502710 
Gene Synonyms/Alias
 Mll3 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
12QKSKQQAKIEATQKLacetylation[1]
18AKIEATQKLEQVKNEacetylation[1]
65KAKMVALKGINKVMAacetylation[1]
754ASSLLTQKPEGTLSSacetylation[1]
836VTRALGPKPFQLPFRacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Methyltransferase; Nucleus; Reference proteome; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1797 AA 
Protein Sequence
QQMRQKSKQQ AKIEATQKLE QVKNEQQQQQ QQQQQQQQQQ LASQHLLDFD AITDPIMKAK 60
MVALKGINKV MAQNSLGMPP MVMSRFPFMG PSMAGVQTSE GQTLMPQAVA QDGSITHQIS 120
RPNPPNFGPG FVNDSQRKQY EEWLQETQQL LQMQQKYLEE QIGAHRKSKK ALSAKQRTAK 180
KAGREFPEED AEQLKHVTEQ QSMVQKQLEQ IRKQQKEHAE LIEDYRIKQQ QQQQQCALAP 240
PILMPGVQPQ PPLVPGASPL TMSQPNFPMV SQQLQHQQHT AVISGHTSPA RMPGLPGWQS 300
SSAPAHLPLN PSRIQPPTAQ LSLKTCTPAP GAVSSANPQN GPPPRVEFDD NNPFSESFQE 360
RERKERLREQ QERQRVQLMQ EVDRQRALQQ RMEMEQHGLM GAELANRTPV SQMPFYASDR 420
PCDFLQPPRP LQQSPQHQQQ IGPVLPQQTV QGSVNSPPNQ TFMQTNERRQ VGPTPFVPDS 480
PSASGGSPNF HSVKQGHGNL SGSSFQQSPL RPPFTPILPG KPPVANSSVP CGQDPAVTAQ 540
GQNFSGSSQS LIQLYSDIIP EEKGKKKRTR KKKKDDDAES SKAPSTPHSD CTAPPTPGLS 600
ETTSAPAVST PSELPQQRQQ EAVEPVRVPT PNVATGQPCI ESENKLPSSE FIKETSSQQT 660
PVSSEADKPS GEASNKSEER KLETAEIQPC PSQEDTKVEE KTGSKIKDTA AGPVSSIQCP 720
SNPARTPVTK GDTGNELLKH LLKNKKASSL LTQKPEGTLS SDESSTQDGK LVEKQNPAEG 780
LQNNLSNPPT PPASLPPTPP PMACQKMANG FATTEELAGK AGVLVSHEVT RALGPKPFQL 840
PFRPQDDLLA RAIAQGPKTV DVPASLPTPP HNNHEELRIQ DHYGDRDTPD SFVPSSSPES 900
VVGVEVNKYP DLSLVKEEPP EPVPSPIIPI LPSISGRDSE SRRNDIKTEP GTLFFTSPFG 960
SSPNGPRSGL ISVAITLHPT AAENISSVVA AFSDLLHVRI PNSYEVSSAP DVPSMGLVSS 1020
HRINPGLEYR QHLLLRGPPP GSANPPRLAT SYRLKQPNVP FPPASNGLSG CKDSSHGIAE 1080
GTSLRPQWCC HCKVVILGSG VRKSFKDLTF ANKGSRESTR RTEKDIVFCS NNCYILHSTT 1140
AQAKISDNKE PLPSLPQSPM KEPSKAFHQY SNNISTLDVH CLPQFQEKVS PPASPPITFP 1200
PAFEAAKVES KPDELKVTVK LKPRLRTVPV GLEDCRPLNK KWRGMKWKKW SIHIVIPKGT 1260
FKPPCEDEID EFLKKLGTSL KPDPVPKDYR KCCFCHEEGD GLTDGPARLL NLDLDLWVHL 1320
NCALWSTEVY ETQAGALINV ELALRRGLQM KCVFCHKTGA TSGCHRFRCT NIYHFTCATK 1380
AQCMFFKDKT MLCPMHKPKG IHEQELSYFA VFRRVYVQRD EVRQIASIVQ RGERDHTFRV 1440
GSLIFHAIGQ LLPQQMQAFH SSKALFPVGY EASRLYWSTR YANRRCRYLC SIEEKDGRPV 1500
FVIRIVEQGH EDLVLSDSSP KDVWDKILEP VACVRKKSEM LQLFPAYLKG EDLFGLTVSA 1560
VARIAESLPG VEACENYTFR YGRNPLMELP LAVNPTGCAR AEPKMSAHVK RPHTLNSTST 1620
SKSFQSTVTG ELNAPYSKQF VHSKSSQYRR MKTEWKSNVY LARSRIQGLG LYAARDIEKH 1680
TMVIEYIGTI IRNEVANRKE KLYESQNRGV YMFRMDNDHV IDATLTGGPA RYINHSCAPN 1740
CVAEVVTFER GHKIIISSNR RIQKGEELCY DYKFDFEDDQ HKIPCHCGAV NCRKWMN 1797 
Gene Ontology
 GO:0005634; C:nucleus; IEA:UniProtKB-KW.
 GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
 GO:0008270; F:zinc ion binding; IEA:InterPro. 
Interpro
 IPR003889; FYrich_C.
 IPR003888; FYrich_N.
 IPR003616; Post-SET_dom.
 IPR001214; SET_dom.
 IPR001965; Znf_PHD. 
Pfam
 PF05965; FYRC
 PF05964; FYRN
 PF00856; SET 
SMART
 SM00542; FYRC
 SM00541; FYRN
 SM00249; PHD
 SM00508; PostSET
 SM00317; SET 
PROSITE
 PS51543; FYRC
 PS51542; FYRN
 PS50868; POST_SET
 PS50280; SET 
PRINTS