CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-010392
UniProt Accession
Genbank Protein ID
 U00089 
Genbank Nucleotide ID
Protein Name
 50S ribosomal protein L1 
Protein Synonyms/Alias
  
Gene Name
 rplA 
Gene Synonyms/Alias
 MPN_220; MP611 
Created Date
 July 27, 2013 
Organism
 Mycoplasma pneumoniae (strain ATCC 29342 / M129) 
NCBI Taxa ID
 272634 
Lysine Modification
Position
Peptide
Type
References
124KFMAALGKLGKLLGTacetylation[1]
139KGLMPNPKTETVTDDacetylation[1]
Reference
 [1] Cross-talk between phosphorylation and lysine acetylation in a genome-reduced bacterium.
 van Noort V, Seebacher J, Bader S, Mohammed S, Vonkova I, Betts MJ, Kühner S, Kumar R, Maier T, O'Flaherty M, Rybin V, Schmeisky A, Yus E, Stülke J, Serrano L, Russell RB, Heck AJ, Bork P, Gavin AC.
 Mol Syst Biol. 2012 Feb 28;8:571. [PMID: 22373819
Functional Description
 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity). 
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome; Repressor; Ribonucleoprotein; Ribosomal protein; RNA-binding; rRNA-binding; Translation regulation; tRNA-binding. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 226 AA 
Protein Sequence
MAKLSKKMKI AVGLVDKTKL YPLQEAVDLV KKTSITKFNG SVDIAVSLNL DTTKAEQQLR 60
GAIAFPHSVG KPIRILAITD DEKAALEAGA DFVGGIDKIN DIKNGWLDFD LIITSPKFMA 120
ALGKLGKLLG TKGLMPNPKT ETVTDDVPAA VRAYKKGKKE YRADSFGNIH MSLGRVDSAS 180
NHLVENALAL LDLIKSRKPA TVKGIYIKNI ALTTTMGPSL KVKLPD 226 
Gene Ontology
 GO:0015934; C:large ribosomal subunit; IEA:InterPro.
 GO:0019843; F:rRNA binding; IEA:HAMAP.
 GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
 GO:0000049; F:tRNA binding; IEA:UniProtKB-KW.
 GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
 GO:0006412; P:translation; IEA:HAMAP. 
Interpro
 IPR005878; Ribosom_L1_bac-type.
 IPR002143; Ribosomal_L1.
 IPR016094; Ribosomal_L1_2-a/b-sand.
 IPR016095; Ribosomal_L1_3-a/b-sand.
 IPR023673; Ribosomal_L1_CS.
 IPR023674; Ribosomal_L1_SF. 
Pfam
 PF00687; Ribosomal_L1 
SMART
  
PROSITE
 PS01199; RIBOSOMAL_L1 
PRINTS