UniProt Accession

 B7Z5W1_HUMAN; B7Z5W1; E7EPV8 

Genbank Protein ID

 AL591806; AK299487 

Genbank Nucleotide ID

 BAH13047.1 

Protein Name

 Junctional adhesion molecule A 

Protein Synonyms/Alias

 cDNA FLJ54854, highly similar to Junctional adhesion molecule A 

Gene Name

 F11R 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
101	LPTGITFKSVTREDT	ubiquitination	[1, 2]
182	IVMPTNPKSTRAFSN	ubiquitination	[3]
281	KKGTSSKKVIYSQPS	ubiquitination	[1]
296	ARSEGEFKQTSSFLV	ubiquitination	[2, 3]

Reference

 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661]
 [3] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Membrane; Reference proteome; Transmembrane; Transmembrane helix. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 303 AA 

Protein Sequence

Gene Ontology

 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. 

Interpro

 IPR007110; Ig-like_dom.
 IPR013783; Ig-like_fold.
 IPR003598; Ig_sub2.
 IPR013106; Ig_V-set.
 IPR003596; Ig_V-set_subgr. 

Pfam

 PF07686; V-set 

SMART

 SM00408; IGc2
 SM00406; IGv 

PROSITE

 PS50835; IG_LIKE 

PRINTS