CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-033484
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Glycerol kinase 
Protein Synonyms/Alias
  
Gene Name
 GK 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
141RDNLGIIKTSEEIEKubiquitination[1]
148KTSEEIEKLAKEVGTubiquitination[2, 3]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [3] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Kinase; Reference proteome; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 354 AA 
Protein Sequence
MLFNIHSLEW DKQLCEFFGI PMEILPNVRS SSEIYGLMKI SHSVKAGALE GVPISGCLGD 60
QSAALVGQMC FQIGQAKNTY GTGCFLLCNT GHKCVFSDHG LLTTVAYKLG RDKPVYYALE 120
GSVAIAGAVI RWLRDNLGII KTSEEIEKLA KEVGTSYGCY FVPAFSGLYA PYWEPSARGI 180
ICGLTQFTNK CHIAFAALEA VCFQTREILD AMNRDCGIPL SHLQVDGGMT SNKILMQLQA 240
DILYIPVVKP SMPETTALGA AMAAGAAEGV GVWSLEPEDL SAVTMERFEP QINAEESEIR 300
YSTWKKAVMK SMGWVTTQSP ESGDPSIFCS LPLGFFIVSS MVMLIGARYI SGIP 354 
Gene Ontology
 GO:0004370; F:glycerol kinase activity; IEA:InterPro.
 GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
 GO:0006072; P:glycerol-3-phosphate metabolic process; IEA:InterPro. 
Interpro
 IPR018485; Carb_kinase_FGGY_C.
 IPR018483; Carb_kinase_FGGY_CS.
 IPR018484; Carb_kinase_FGGY_N.
 IPR005999; Glycerol_kin. 
Pfam
 PF02782; FGGY_C
 PF00370; FGGY_N 
SMART
  
PROSITE
 PS00445; FGGY_KINASES_2 
PRINTS