CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-036780
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Centrin-3 
Protein Synonyms/Alias
  
Gene Name
 CETN3 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
13RSELVVDKTKRKKRRubiquitination[1]
15ELVVDKTKRKKRRELubiquitination[1]
62RALGFDVKKADVLKIubiquitination[1]
63ALGFDVKKADVLKILubiquitination[1]
68VKKADVLKILKDYDRubiquitination[1]
71ADVLKILKDYDREATubiquitination[1]
108EEILKAFKLFDDDDSubiquitination[2, 3]
117FDDDDSGKISLRNLRubiquitination[1, 2, 3]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [3] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 191 AA 
Protein Sequence
MSLALRSELV VDKTKRKKRR ELSEEQKQEI KDAFELFDTD KDEAIDYHEL KVAMRALGFD 60
VKKADVLKIL KDYDREATGK ITFEDFNEVV TDWILERDPH EEILKAFKLF DDDDSGKISL 120
RNLRRVAREL GENMSDEELR AMIEEFDKDG DGEILKNILL LPIWSRCLSL NREFFSEVNQ 180
EEFIAIMTGD I 191 
Gene Ontology
 GO:0005737; C:cytoplasm; IDA:HPA.
 GO:0045111; C:intermediate filament cytoskeleton; IDA:HPA.
 GO:0005509; F:calcium ion binding; IEA:InterPro. 
Interpro
 IPR011992; EF-hand-like_dom.
 IPR002048; EF_hand_dom. 
Pfam
 PF13499; EF_hand_5 
SMART
 SM00054; EFh 
PROSITE
 PS50222; EF_HAND_2 
PRINTS