| Tag | Content |
|---|
| CPLM ID | CPLM-014919 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Erythroid differentiation-related factor 1 |
Protein Synonyms/Alias | |
Gene Name | Edrf1 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 660 | QMALFLDKMGSIQKG | ubiquitination | [1] | | 694 | QLILKSSKAYYILSD | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Transcription factor involved in erythroid differentiation. Involved in transcriptional activation of the globin gene (By similarity). |
Sequence Annotation | REPEAT 693 726 TPR 1.
REPEAT 914 953 TPR 2. |
Keyword | Activator; Complete proteome; Nucleus; Reference proteome; Repeat; TPR repeat; Transcription; Transcription regulation. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 1239 AA |
Protein Sequence | MGDPKEAGAE ASPSGAAARG GLSLLSQADS EEPSAQGSAL FLGGNEVKSR AVVKYSSAPP 60
RTAFARLEEK TDLKLPPANW LRESAKLGPA GTTILGNSKK SKPFSSFGMA YDFIDSVGND 120
VDVVSDSENI KKLLKIPYSK SHVSMAVHRI GRTLLLDELD IQELFMRSSQ TGDWTWLKEF 180
YQRLIDQKWQ RKKKSKEHWY QKAILSKFLY YSINGDGAAQ PVPSPAEQEE SSSSQQTHES 240
EGAAWPAPFE MPSSVSEDPS ASSQGREPLE PSCIVGHVAS APKEQNLTTL FNDGENSQGL 300
KNDFVRNILW TFEDIHMLVG SNMPIFGGGR YPAVSLRLRD NNKPINVLTG IDYWLDNLIC 360
NVPELVMCFH VNGIVQKYEM IKTEEIPNLE NSNFSTKVIK DIAQNILSFL KSNCTKEGHT 420
YWLFKASGSD IVKLYDLTTL CEETEDKYQN PFTMPVAILL YKVACNMMMK KNQNKKHYGT 480
IRTLLLNCVK LLDKSRHPQI IASANYMLSE LFQLDEPKKE ESSDSPLNEN SDESYSEEEE 540
EMADSDENGS YSTSSDPADD NKAVAIIKSV GELSVPEKYK SIHQIRPSCA FPVCHDTEER 600
CRLVLSYVLE GLKSVDSSIK KESDLPAADP STPIPLKYED ESTRGGPEGL EKQMALFLDK 660
MGSIQKGSCS GQSGMTPGSW QHKMKLQLIL KSSKAYYILS DAAMSLQKYG RALRYIKLAL 720
QSHDTYCCLC TNMLSEVLLF LSQYLTLCGD IQLMLAQNAN NRAAHLEEFN YQTKEDQEIL 780
HSLHRESSCQ GFAWATDLST DLESQLSVSC KCYEAANEIL QFSDLKSQNP EHYVQVLKRM 840
GNIRNEIGVF YMNQAAALQG ERVVSKSVSA AEQQLWKKSF SCFEKGIHNF ESIDDATNAA 900
LLLCNTGRLM RVCAQAHCGA EDEFKREFSP EEGLYYSKAV DYYLKALRSL GTRDMHPIVW 960
DSVNWELSTT YFTMATLQQD YAPLSRKAQE QIEKEVSEAM MKSLKHCDVD SATARQPLCQ 1020
YRAATIHHRL ASMYHSCLRN QVGDEHLRKQ HRVLADLHYS KAAKLFQLLK DAPCELLRVQ 1080
LERVAFAEFQ MSSQNSNVGK LKTLSGALDI MVRTEHAFQL IRKELVEECD QPKNDEATPA 1140
ADSSPNLNRE EVIKLLSIFE SRLSFLLLQS IKLMSSSKRK MSSNAEEDIV LQTNKQIYSQ 1200
LLRATANRNS TLLERIEVVI CLLEQLASGS SRSSGSAVP 1239 |
Gene Ontology | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW. GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |