CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-008672
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Clathrin coat assembly protein AP180B 
Protein Synonyms/Alias
  
Gene Name
 YAP1802 
Gene Synonyms/Alias
 YGR241C; G8610 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
136RDNYSSLKLGSKNQLubiquitination[1]
282SEPQQDRKPSTAISSubiquitination[1, 2]
300HNNNSNDKNKSIAQKubiquitination[1]
Reference
 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301]
 [2] Sites of ubiquitin attachment in Saccharomyces cerevisiae.
 Starita LM, Lo RS, Eng JK, von Haller PD, Fields S.
 Proteomics. 2012 Jan;12(2):236-40. [PMID: 22106047] 
Functional Description
 Involved in endocytosis and clathrin cage assembly. 
Sequence Annotation
 DOMAIN 1 127 ENTH.
 MOD_RES 449 449 Phosphothreonine.  
Keyword
 Cell membrane; Complete proteome; Cytoplasm; Endocytosis; Membrane; Phosphoprotein; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 568 AA 
Protein Sequence
MSSLYTKLVK GATKIKMAPP KQKYVDPILS GTSSARGLQE ITHALDIRLS DTAWTIVYKA 60
LIVLHLMIQQ GEKDVTLRHY SHNLDVFQLR KISHTTKWSS NDMRALQRYD EYLKTRCEEY 120
GRLGMDHLRD NYSSLKLGSK NQLSMDEELD HVESLEIQIN ALIRNKYSVS DLENHLLLYA 180
FQLLVQDLLG LYNALNEGVI TLLESFFELS IEHAKRTLDL YKDFVDMTEY VVRYLKIGKA 240
VGLKIPVIKH ITTKLINSLE EHLREETKRQ RGEPSEPQQD RKPSTAISST SSHNNNSNDK 300
NKSIAQKKLE QIREQKRLLE QQLQNQQLLI SPTVPQDAYN PFGSQQQDLN NDTFSFEPTQ 360
PQMTAQVPQP TANPFLIPQQ QQQALQLTSA STMPQPSEIQ ITPNLNNQQT GMYASNLQYT 420
PNFTGSGFGG YTTTENNAIM TGTLDPTKTG SNNPFSLENI AREQQQQNFQ NSPNPFTLQQ 480
AQTTPILAHS QTGNPFQAQN VVTSPMGTYM TNPVAGQLQY ASTGAQQQPQ MMQGQQTGYV 540
MVPTAFVPIN QQQQQQQHQQ ENPNLIDI 568 
Gene Ontology
 GO:0030479; C:actin cortical patch; TAS:SGD.
 GO:0005935; C:cellular bud neck; IEA:UniProtKB-SubCell.
 GO:0030118; C:clathrin coat; IEA:InterPro.
 GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
 GO:0005545; F:1-phosphatidylinositol binding; IEA:InterPro.
 GO:0030276; F:clathrin binding; TAS:SGD.
 GO:0048268; P:clathrin coat assembly; IEA:InterPro.
 GO:0006897; P:endocytosis; IPI:SGD. 
Interpro
 IPR011417; ANTH_dom.
 IPR014712; Clathrin_Pinositid-bd_GAT-like.
 IPR008942; ENTH_VHS.
 IPR013809; Epsin-like_N. 
Pfam
 PF07651; ANTH 
SMART
 SM00273; ENTH 
PROSITE
 PS50942; ENTH 
PRINTS