CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-006308
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Beta-glucan synthesis-associated protein SKN1 
Protein Synonyms/Alias
  
Gene Name
 SKN1 
Gene Synonyms/Alias
 YGR143W 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
115GQRMSDYKGYYAKTNubiquitination[1]
120DYKGYYAKTNLTSANubiquitination[1]
209SQNLINEKKRANMTGubiquitination[1, 2]
368PDTPDSAKTRVAKDGubiquitination[1]
Reference
 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301]
 [2] Sites of ubiquitin attachment in Saccharomyces cerevisiae.
 Starita LM, Lo RS, Eng JK, von Haller PD, Fields S.
 Proteomics. 2012 Jan;12(2):236-40. [PMID: 22106047] 
Functional Description
 Required for synthesis of the major beta-glucans of the yeast cell wall. 
Sequence Annotation
 MOD_RES 56 56 Phosphoserine.
 MOD_RES 65 65 Phosphoserine.
 MOD_RES 67 67 Phosphoserine.
 MOD_RES 103 103 Phosphoserine.
 MOD_RES 176 176 Phosphoserine.
 CARBOHYD 337 337 N-linked (GlcNAc...) (Potential).
 CARBOHYD 426 426 N-linked (GlcNAc...) (Potential).
 CARBOHYD 513 513 N-linked (GlcNAc...) (Potential).
 CARBOHYD 590 590 N-linked (GlcNAc...) (Potential).
 CARBOHYD 615 615 N-linked (GlcNAc...) (Potential).
 CARBOHYD 743 743 N-linked (GlcNAc...) (Potential).  
Keyword
 Cell wall biogenesis/degradation; Complete proteome; Glycoprotein; Membrane; Phosphoprotein; Reference proteome; Signal-anchor; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 771 AA 
Protein Sequence
MSVRNLTNNR HSNSENSVSG SENSFYSSNE QSRQSSSLEP ADGQNVRVSG NPFLGSEEFD 60
EDYNSPSGDD ERRGANEYSS SSSINYNNDP NSDTSLLANE KNSPERNGQR MSDYKGYYAK 120
TNLTSANNLN NHNNNNYKNI ISSSNDNSFA SHLQPPDRNL PSHPSSNNMS SFSNNSLIKS 180
PPPFDRYPLV GTRHISAAQS QSQNLINEKK RANMTGSSSS AHDSSLSSTN LYMGEQDFSP 240
FGGYPASFFP LTLDEKEDDD YIHNPNVEEE AKLDRRRFVD DFKHMDRRSF LGLLGILFLF 300
MAGIFIFIVL PAITFSGVVY HHEHVHAANS AGSSSSNTTS KSLTEYQYPQ LAAIRTTLVD 360
PDTPDSAKTR VAKDGSKWQL VFSDEFNAEG RTFYDGDDQF WTAPDIHYDA TKDLEWYSPD 420
AVTTTNGTLT LRMDAFRNHD LYYRSGMVQS WNKLCFTEGA LEVSANLPNY GRVTGLWPGM 480
WTMGNLGRPG YLASTQGVWP YSYEACDAGI TPNQSSPDGI SYLPGQKLSV CTCDNEDHPN 540
QGVGRGAPEI DILEGEADTI LGVGVASQSL QIAPFDIWYM PDYDFIEVYN FTTTTMNTYA 600
GGPFQQAVSA ISTLNVTWYE FGEEAGYFQK YAIEYLNDDD NGYIRWFVGE NPTFTLYATS 660
LHPSGNIDWR RISKEPMSAI LNLGISNNWA YIDWQYIFFP VTMSIDYVRL YQPKGSTSIT 720
CDPEDYPTYD YIQSHLNAYY NANLTDWEQA GYTFPKNILT GGCSSSKFSL S 771 
Gene Ontology
 GO:0016021; C:integral to membrane; IDA:SGD.
 GO:0015926; F:glucosidase activity; IMP:SGD.
 GO:0006078; P:(1->6)-beta-D-glucan biosynthetic process; IMP:SGD.
 GO:0031505; P:fungal-type cell wall organization; IMP:SGD.
 GO:0030148; P:sphingolipid biosynthetic process; IMP:SGD. 
Interpro
 IPR008985; ConA-like_lec_gl_sf.
 IPR013320; ConA-like_subgrp.
 IPR005629; SKN1. 
Pfam
 PF03935; SKN1 
SMART
  
PROSITE
  
PRINTS