UniProt Accession

 B7Z1C2_HUMAN; B7Z1C2 

Genbank Protein ID

 AC007570; AK293130; CH471054 

Genbank Nucleotide ID

 BAH11458.1; EAW97870.1 

Protein Name

 Mevalonate kinase 

Protein Synonyms/Alias

 Mevalonate kinase (Mevalonic aciduria), isoform CRA_a; cDNA FLJ57872, highly similar to Mevalonate kinase (EC 2.7.1.36) 

Gene Name

 MVK 

Gene Synonyms/Alias

 hCG_40321 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
44	QILLTNTKVPRNTRA	ubiquitination	[1]
151	GCGITLLKPGLEQPE	ubiquitination	[1]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Kinase; Reference proteome; Transferase. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 202 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IDA:HPA.
 GO:0005524; F:ATP binding; IEA:InterPro.
 GO:0004496; F:mevalonate kinase activity; IEA:Compara.
 GO:0008299; P:isoprenoid biosynthetic process; IEA:InterPro. 

Interpro

 IPR013750; GHMP_kinase_C_dom.
 IPR006205; Mev_gal_kin.
 IPR014721; Ribosomal_S5_D2-typ_fold_subgr. 

Pfam

 PF08544; GHMP_kinases_C 

SMART

  

PROSITE

  

PRINTS