UniProt Accession

 PTH2_MOUSE; Q8R2Y8; Q8BI01; Q8BI31 

Genbank Protein ID

 AK028555; AK031620; AK038888; BC026947 

Genbank Nucleotide ID

 BAC26006.1; BAC27482.1; BAC30159.1; AAH26947.1 

Protein Name

 Peptidyl-tRNA hydrolase 2, mitochondrial 

Protein Synonyms/Alias

 PTH 2 

Gene Name

 Ptrh2 

Gene Synonyms/Alias

 Pth2 

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
83	DLKMGKGKVAAQCSH	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity). 

Sequence Annotation

  

Keyword

 Complete proteome; Hydrolase; Mitochondrion; Reference proteome; Transit peptide. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 181 AA 

Protein Sequence

Gene Ontology

 GO:0005829; C:cytosol; IEA:Compara.
 GO:0005739; C:mitochondrion; IDA:MGI.
 GO:0004045; F:aminoacyl-tRNA hydrolase activity; IEA:EC.
 GO:2000811; P:negative regulation of anoikis; IEA:Compara.
 GO:0010629; P:negative regulation of gene expression; IEA:Compara.
 GO:2000210; P:positive regulation of anoikis; IEA:Compara. 

Interpro

 IPR023476; Pep_tRNA_hydro_II_dom.
 IPR002833; Pep_tRNA_hydro_PTH2. 

Pfam

 PF01981; PTH2 

SMART

  

PROSITE

  

PRINTS