| Tag | Content |
|---|
| CPLM ID | CPLM-016494 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | 26S proteasome non-ATPase regulatory subunit 5 |
Protein Synonyms/Alias | 26S protease subunit S5 basic; 26S proteasome subunit S5B |
Gene Name | Psmd5 |
Gene Synonyms/Alias | Kiaa0072 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 143 | GENLSVAKAAIKSLS | ubiquitination | [1] | | 147 | SVAKAAIKSLSRISL | ubiquitination | [1] | | 467 | VKALANSKTVAEIFG | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Acts as a chaperone during the assembly of the 26S proteasome, specifically of the base subcomplex of the PA700/19S regulatory complex (RC). In the initial step of the base subcomplex assembly is part of an intermediate PSMD5:PSMC2:PSMC1:PSMD2 module which probably assembles with a PSMD10:PSMC4:PSMC5:PAAF1 module followed by dissociation of PSMD5 (By similarity). |
Sequence Annotation | MOD_RES 2 2 N-acetylalanine (By similarity). |
Keyword | Acetylation; Chaperone; Complete proteome; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 504 AA |
Protein Sequence | MAAQAVSLLR EVARLEAPLE ELRALQSVVQ AVPLHELREQ AAELRLRPLF SLLNQNNREQ 60
TALCVSILER LLQAVEPIHL ARNLRLDLQR GLTHPDDSVK TLTLSQIGRI VENSEAVTEI 120
LNNAELLKQI VYCIGGENLS VAKAAIKSLS RISLTQAGLE ALFESNLLDD LKNVMKTNDV 180
VRYRVYELII DISSVSSESL NYCTTSGLVT QLLKELTGED VLVRATCIEM VTSLAYTHHG 240
RQYLAQEGVI DQISNIIVGA DSDPFSGFYL PGFVKFFGNL AVMDSPQQIC ERYPVFLEKV 300
FEMADSQDPT MIGVAVDTVG ILGSSVEGKQ VLQKTGTRFE RVLMRVGYQA KNASTELKIR 360
CLDAVSSLLY LSPEQQTDDF LGMTESWFSS MSRDSLELFR GISNQPFPEL HCAALKVFTA 420
IADQPWAQRL MFNSPGFVEF VMDRSVEHDK ASKDAKYELV KALANSKTVA EIFGNSNYLR 480
LRAYLSEGPY YVKPVATTAV EGAD 504 |
Gene Ontology | GO:0022624; C:proteasome accessory complex; IDA:UniProtKB. GO:0008540; C:proteasome regulatory particle, base subcomplex; IEA:Compara. GO:0006457; P:protein folding; IEA:GOC. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |