UniProt Accession

 CKAP4_MOUSE; Q8BMK4; B2RRB4; Q8BTK8; Q8R3F2 

Genbank Protein ID

 AC140333; AC150314; BC025522; BC138318; BC138320; AK030708; AK089935 

Genbank Nucleotide ID

 AAH25522.1; AAI38319.1; AAI38321.1; BAC27092.1; BAC41005.1 

Protein Name

 Cytoskeleton-associated protein 4 

Protein Synonyms/Alias

 63-kDa cytoskeleton-linking membrane protein; Climp-63; p63 

Gene Name

 Ckap4 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
21	GAASPSDKGAHPSGG	acetylation	[1]
185	RISEVLQKLQNEILK	acetylation	[2]
192	KLQNEILKDLSDGIH	acetylation	[2]
202	SDGIHVVKDARERDF	acetylation	[3]
312	VRELVSLKQEQQAFK	acetylation	[1, 2]
312	VRELVSLKQEQQAFK	succinylation	[1]
335	ALQALTEKLLRSEES	acetylation	[2]

Reference

 [1] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337]
 [2] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441]
 [3] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 

Functional Description

 High-affinity epithelial cell surface receptor for APF (By similarity). 

Sequence Annotation

 MOD_RES 3 3 Phosphoserine (By similarity).
 MOD_RES 17 17 Phosphoserine (By similarity).
 MOD_RES 19 19 Phosphoserine (By similarity).
 MOD_RES 292 292 Phosphoserine (By similarity).
 LIPID 79 79 S-palmitoyl cysteine; by ZDHHC2 (By  

Keyword

 Cell membrane; Coiled coil; Complete proteome; Cytoplasm; Cytoskeleton; Endoplasmic reticulum; Lipoprotein; Membrane; Palmitate; Phosphoprotein; Reference proteome; Signal-anchor; Transmembrane; Transmembrane helix. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 575 AA 

Protein Sequence

Gene Ontology

 GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
 GO:0005783; C:endoplasmic reticulum; IDA:MGI.
 GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005811; C:lipid particle; IEA:Compara.
 GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
 GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. 

Interpro

  

Pfam

  

SMART

  

PROSITE

  

PRINTS