CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-032647
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 PHD-finger domain-containing protein, putative 
Protein Synonyms/Alias
  
Gene Name
 TGVEG_065010 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Toxoplasma gondii 
NCBI Taxa ID
 5811 
Lysine Modification
Position
Peptide
Type
References
2810ATDEETGKQSCSREGacetylation[1, 2]
3138CSQHAKNKAPTLILRacetylation[2]
3476AAHKEPQKEAEVSCLacetylation[2]
4886VAWESGSKRRRVSLSacetylation[1, 2]
4956VTPLESQKRVIDPARacetylation[1, 2]
5026RDTGKALKFTQDAGNacetylation[1]
5286DKHRSGIKHSRSRPPacetylation[1, 2]
Reference
 [1] Lysine acetylation is widespread on proteins of diverse function and localization in the protozoan parasite Toxoplasma gondii.
 Jeffers V, Sullivan WJ Jr.
 Eukaryot Cell. 2012 Jun;11(6):735-42. [PMID: 22544907]
 [2] Protein intrinsic disorder in the acetylome of intracellular and extracellular Toxoplasma gondii.
 Xue B, Jeffers V, Sullivan WJ, Uversky VN.
 Mol Biosyst. 2013 Apr 5;9(4):645-57. [PMID: 23403842
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Metal-binding; Reference proteome; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 5302 AA 
Protein Sequence
MQRAARQSRG RSGGRAGGGG GEGASGSLGD RGCSDTEEER FWIEKDVEFF SAINPRLLAL 60
LHHHKQSSEA FLSAVLPYLR SRSRKDAADA AGPSPRSEAA QAFALRVPVR DFLRQDWTGG 120
EIGGSVLSGS SSEERRDRRR EEIIERDSDP PKRVASSPPC RSRSVEENLT ERAVFSRDGR 180
SICSKDPQGA REEASPSCDS LSSPVRRSSS ASCLGISQPV SSEAGSEAGS SSVFASGATA 240
VAAGFARTVP TSSRKGAASE GGENSPRSEG GNSVSSRVCS SQGSAPAPVV GCQAHPAPSR 300
LSQVWPHHTG KILLERPSYS GETGRVIRHM WPATLLADVE PSALCPPPLL RSKKAAADPK 360
KKDDSRAYVR TGVEKKNLEE SSRLSCGTEE TESRGESQKR SPDGGRSSQP HSSSVSADLK 420
ETNRETAESQ ADGSKTDAGL GLCSPWSEET GKTEEEKKDV ESQPCGDAGG GRKDREEDRG 480
REETPQRSSG AVKEETNASG EGRPPSGPQS PSKHLDQPVR AAWESSNPRI LNGETGSRDG 540
EDSSSSCPEV GTQGPRPTSR RSSVEGRERR SAGLRAASDD KTEKSEDSRE KEKDLGAPQP 600
SKDSQEGQAA SVEATLQNTR TGAPSRAVPT TVLSGVKREL EQDGDTQGPR CGARSPCRAS 660
ETSPRDEPMS RPAGQTSSEK WKREEAFCLQ VSQNRSIFSL VPGANDPALL ASLHEHQLHA 720
HLKYQSRDLS VFSHSGDFKR RAASARGVSR RSGGRRGTRL AAGFDCEETA EGDFSSGSLA 780
SSTPSSPAAR AAGARERERN RRGSDSDFTP SRSEKGDARG DRPAAARRRD GVSGTVHQKA 840
GSGSPGPSRA GREEVRAGGR TPSGEREPTQ RSSSVGREAK AVVEGGEEDP DEAGADDLFV 900
PTVHKKWNGS MRLPAFPTCR PPDAFVLSMF VPPNVSPADF PEDTNAQGDV SAFLAVVMEA 960
ATTTASDWDA HANTFTPHDG YNLAEKPGDC GPVRALGKVT AERLGAERNR GTEGLGLVSR 1020
EACRRHLLTT AGSCDMQETS QVGSGDSVAQ VEAERRAQLE RSFACEGSEA RPGHARPVAS 1080
EHPSASHRRD LSKDGGLVKT PGGGRRRRRS SSTGSGGERT NSGNRRRLKD EKKRSSGTGA 1140
PVSPQPRSSS GRFMSRQSLT EVSPAAPTSS KPRASVSPSS SLALVSASPR KRPRRRLPLP 1200
TVLSGPLPAW IDCSERFPGP APIVHGPRGP SGPFNAGLSF SASHGSCGGQ ASGLGMPGPC 1260
WGRPVWPETG APFHISGDED PGRAGMNGKR ALDKGSETRG GKASDEKREQ SQAESEARLP 1320
SSSTTNASPP KHDPPCSSSP PPAERSCPRL DAEGMRSSHA LFPPGQSYGG LSPGTQASGC 1380
SPSPGASFSR ASPAGPSSPG STSSGVHPSQ SFASPPSSCP PFAFSGTGPA APYLASGCHP 1440
CSFSVRPPAC GAAAAFSPAS PYAPCRPCAY LPQDASSGPP PQISGTAYPG AALLSPPSSA 1500
PPGPVCAGPV SEAFSSVRHS FPAACCPPHP CPPFSSCPPG HPQFCAPGNP FSSYPSEMSA 1560
FPELQRFSSA PPPPCTSFNC PPPYPPPACF PPAPESSSSS VSSADFVASF SSSPGPCRRA 1620
SSAFSGSTPS EKSEEPSGVS SCQNLGSDAT HPPCFSGPTY PVLGGPVDTA FCRPPPSTAP 1680
PGSVPFAAFP PFPCPPLLGL GPVSEFEDRG PVLRSFPFGP ASSPAYLTLS LFPRPSLPAF 1740
PGSAAPFEPV SRCSSFLPRG ELQTVSSSPP ESVASCLPTP PPEILVPPFF GAESSLKPFP 1800
PPCCLYPPEM AENFRYSEKR KMMVPSGVRL ELLRAQMTRV DGLHTFYANV ETGKRFFGER 1860
SFFEIAKENA RRHDAGLQPL SLSPLTSNSA TAFFMSVAPE TEIPPSGSPT GPHTAPKKTK 1920
ATKEDSEREE REKREREERE KRERDEERGR RDLEEKIRIH MYSRHMVPAG SPHLSGAHRL 1980
IPLPWGKRDA SRSSPQELEI RARDGDCFHA SSGASAGVGG PQEKKGKTED AQGEQLVSLE 2040
TAAEPETQEK KETKARGVAG VGPSAQSAET ASPAPEAACD GQSAEVSPRG DSAAGRAETG 2100
PACGVTGERR EVDRESAQDE GKETEVKTEG AEGACETGDF TGCVSVEEGE GCGVKEVTEK 2160
AKEGCASDAA NGGTRREQSE KEPGRDKDRV GGMHTPFLSE GGEKENREEN GDDRESADPV 2220
SLKEFNKHRQ TSKRVGDVAE PERAKEENAC PREQAESEAM DVDSPEARGE LLEGRKDFEV 2280
LSSRNATETA DFDTRQNEKQ KAKGTLVTST SFGTEVENLL WRFSALMDEK RAMCSRLLMS 2340
IEREKRPDWR AWAEVEDRML RHYIEQSAKS SLDTRHTYTL TQQSRDILRL RVSCSSSGRL 2400
PPEWAERALC TVCGSGEDWD EDPIMFCDGC YQPVHFLCLG HKAVSSYEEF VKASTTRRQR 2460
RVAQAGGDQG LAPATARERG SGPKRDKKKA AERAKEEKKK GRGGTGDLLA SGAFGASALG 2520
AGSGDAPGAS RPAEGDPSGP GASPGDTGHN TRRPVCGAGG FAFREDEEEW LCPVCEWLRK 2580
QLPQLDDELA LAAIRLAAGP RSHSEAAECR GSYVGWHFER LEHFDSWVKP QLLALQYGDG 2640
RRRKGKGRLQ VDVGAPQGSR KDTRQGRKVA TGLGLPSGDA DSVSTLQAHS AYSVQELLAW 2700
PAVRVVADAS CLGPNAQSSR SSTSRGSAAR GPGTAGETGG VAGSGGDGSG VFRAEKDEED 2760
RGLKKPELDE SGGRPSIRGA GPKPCISSLA QTMLGARTLP VWATDEETGK QSCSREGSVA 2820
GSKGGRLAAD GRRLGGGERA GDRCVEPEED DARRAKGDGD FGRDAWTRGF RSGSETGMGT 2880
SGKGAREKHP VSLVAPEDAT PATDYIRRVP YAFSDSSGDE GPSGKDGDTP FFFCQYTAGS 2940
PTASSPSSAA HRTPSQEDDN QGGLFSGSAF SPSSASMRSG AHASGGFSPN SAEPGASLTS 3000
KHYCSKDPRR RCVVRVFPVP GLSVVLRVPV CALCGYDAFC RGGGPARKTE KKGVWAHLRC 3060
ALSLNATVMD RVSYEADESR SRLRCLFCHH QGPAPGHCGH AGCQRTYHVS CATATPGCMV 3120
DWDMGRPVIF CSQHAKNKAP TLILRKFQAN REREAVKRRE EDLPGEWKIG VGKGRLGIAL 3180
QSLLFPSYDG LCNVFSDLLE VPTLRLPTLS PAEKKVTSQG LEALSFPGAD PALGAPRDEA 3240
EALERRHRAQ SREEKATGVD EQRRGNAQTE DAAHREKEEK GRNLEGSSVA RGEAESGGGP 3300
DEEEERFTRR LTWRRRRVAD SDAEDLEGKE TKKKCPEEKA AGRTAEGADA SVETSRDCGM 3360
EGESASTAHE KQEVLDAGEL RRETEGDSSP PSHSPKNVMV GEGVDNSRVS RASLEEQEWK 3420
KEKAEEKERR NWEKPEVIQS GLPSGEREEV CQSVGAAASR EQGLSGSHAA HKEPQKEAEV 3480
SCLSSTRDMT RVREAREEPT FENRGKNDQT KPAEAEDRGN VRVDEFRLSR SPENESRLLS 3540
SLQKDRDEDR MEESENRLAG ARGTGESRSD PTSASSSSAV NTVAGADAGR EVENVVAENC 3600
SSPSSFPGGQ DDTLSFVLQE RERSEAAAVL GKSESATDAV AGEGEGRERS RQSPNGCGAG 3660
EEARDDESRL DRQSGSTTDA PPLFLPSGSS DLLSLPPSSR LGETAGRCLP NGPAPPGEGV 3720
SEPVSSRVGS VLEGETGARR GECVSHSQAG TSREQGGVSR GESDTATPFS SGGETGASHA 3780
DEKPQRGPHS SLNSFAALDL EGGRTQNAAP GHKGTLASPT GVAAPFGDPL ENSPQNLFEA 3840
NASKSPFSPD GWGEAAFFSS ASSFRSFSFT SGNPPGSSSE PAAPPRKRRG RPPLSRRSQG 3900
ATHKDAVHRQ DRDRVSSYLK MAAGGALSRG GRFSLGGSCD RDKRRSLHLG GGRGSGMNLP 3960
ERGPGGRFLP RGHREKNAQQ TPVSDSVSTS SYQKQRPVSL SDPSQEGSAD RRDGGDSGGE 4020
NESQENRELQ AREEALHQQR MRYMQMLFHL QALTRERHRR LLGNDFALTG LLLGSPDPAG 4080
AFDPGALHAA GLPPTPLHGS SPATFFARRV ARLLDSPAPL AIRRSSTNGS TGTAGEEKVR 4140
GAPGGVGQAD TATVETGVEE GPSGRAGAER GTGGAQEEND EKEEKKESVS GVSSCAADAN 4200
PDAGNRAKEA RTKEASACVA LASFSSPVDY LRLTTIKDWG LPQHTGDEKL FKCAFEETKA 4260
ADVLGIETYD RFLARQGVQS VARLLDAVVD LLLFFILRGV CCAGPSPALL AALSEGKSLP 4320
QSRVPGGFVF PLALQLPGGS PAGGQKAKRA ERPGGSERPC EAEEETEDSQ REGKTPSAPP 4380
ACSEEEPLYA LIDTVRQLGQ VAELDFKTGT DAIQKEEGAK KQLAVKREEP SVGTDDDEDE 4440
DELDEMKKRR SRTKQEKNAI ATRRRQTSAE RDREQEMQER LREEDETDWT CLRCAAVLNV 4500
GTPFPSTRCI LCSRIDGLLV RRIPEDTPSL SNKKSGAFHV SCARQLGCRM ETQRRSLDQQ 4560
IHRAYCLEHT TQMNRKLLQQ RLASHKPFAF PQRKDTLDLN RFFDPLQLLI ADPIRSITSL 4620
FLVGIHLERL APPSLTSFAA FMRPSSLRLS SAEGGKQGEK EKRCREAFGA RGALHTSGRV 4680
DEQRARYLKT GTHRPEETGS VSWNAFDEND AFFEAVRERK KQRHGRREEG VGERTRTGAS 4740
AWSEGEREGR RERGLESGDD YAASSACDPL LTPGPPSPLH LEEQRELYCT GVAICDALYT 4800
QSRAFEEEAL NLPSPSRSEV DAARALYCVS EPASPDLRDR QRWTSAFEVT DGLMDDENEK 4860
TTAGRTSSGS TSLERGRGVA WESGSKRRRV SLSSGSGGPP YFSGDALSSV KDRVPPSCLT 4920
RSGLRSSLVS AAHASHFFDA GEDRGNQLVT PLESQKRVID PARLTWSPQE SVRRPSFVAR 4980
AGLDGAVCLH DGGEALPAPA LTLSAEDSEA PTEEKRQSRD TGKALKFTQD AGNESSEKES 5040
RFSPDQSLPH SDAESSGANA WGVSPSPALP SDGDSSGPRA TASQTVSAVS CDSESIVLPP 5100
YLLRGTAVDL PSLTEDVSPA ASASAVLASE SWYRGISAAA SMAVAHAVQA VSSRGDLDAD 5160
EAEGAARERE EKQNGESFDV LANLHIGSPG QVQGEKQPIF CPICKGMYNE LPDGGPGDGF 5220
AWVGCDCCER WYHWTCSGFN EENPPPDDCD WICWFCTVKI RKKEEQERER QAHGLQVKDK 5280
HRSGIKHSRS RPPPRKRDRS KR 5302 
Gene Ontology
 GO:0008270; F:zinc ion binding; IEA:InterPro. 
Interpro
 IPR019786; Zinc_finger_PHD-type_CS.
 IPR011011; Znf_FYVE_PHD.
 IPR001965; Znf_PHD.
 IPR019787; Znf_PHD-finger.
 IPR001841; Znf_RING.
 IPR013083; Znf_RING/FYVE/PHD. 
Pfam
  
SMART
 SM00249; PHD
 SM00184; RING 
PROSITE
 PS01359; ZF_PHD_1
 PS50016; ZF_PHD_2 
PRINTS