CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-030336
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Dimethylaniline monooxygenase [N-oxide-forming] 
Protein Synonyms/Alias
  
Gene Name
 Gm4846 
Gene Synonyms/Alias
 EG226601; mCG_3604 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
479YRLQGPGKWAGARAAacetylation[1]
479YRLQGPGKWAGARAAubiquitination[2]
Reference
 [1] Quantification of mitochondrial acetylation dynamics highlights prominent sites of metabolic regulation.
 Still AJ, Floyd BJ, Hebert AS, Bingman CA, Carson JJ, Gunderson DR, Dolan BK, Grimsrud PA, Dittenhafer-Reed KE, Stapleton DS, Keller MP, Westphall MS, Denu JM, Attie AD, Coon JJ, Pagliarini DJ.
 J Biol Chem. 2013 Jul 17;. [PMID: 23864654]
 [2] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Endoplasmic reticulum; FAD; Flavoprotein; Membrane; Microsome; Monooxygenase; NADP; Oxidoreductase; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 538 AA 
Protein Sequence
MEVKQIAIIG AGVSGLGAIK SCLEEGLEPT CFEKSNDIGG LWRYKETPEN GRPGIYKSLT 60
CNTSKEMTTF SDYPIPDHYP NYMHHSKMME YLRMYARHFG LMKHIQFQTR VCVVRKRPDF 120
SSSGQWDVVV EADGKQKNYI FDGVMVCSGH YTEKYLPLQD FAGISKFQGS CLHSWEYKHP 180
DSFVGKRVVV IGIGNSGADV ANEISCVTEQ VFLSTRRGTW IWNRVWDNGD PLDIALFTRY 240
NRTVKSFYPT FLINRWTENK LNLRFNHANY GLQAKHRFLS HQSIFSDDLP NRIISGRVLV 300
KTNVREFTST SAIFEDGSEE IVDVVVFATG YTLSFPFLDD SSEILDSKHT MFKFVFPPQL 360
EKPTLAFIGI LQPIGATIPT SELQSRWVTR VFAGLQKLPS QSNMMADINR KKRKMEKEFV 420
KSPRDVRRVP YIDYMDEIAS EIGVKPNLLS FFLWDTKLAK EIFWGPCTPY QYRLQGPGKW 480
AGARAAILTQ RDRILKPLRS RVLKNSETSS SSLFWVRCIC AVIFPFVSVF AIIHAIYQ 538 
Gene Ontology
 GO:0031227; C:intrinsic to endoplasmic reticulum membrane; IEA:InterPro.
 GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
 GO:0004499; F:N,N-dimethylaniline monooxygenase activity; IEA:EC.
 GO:0050661; F:NADP binding; IEA:InterPro. 
Interpro
 IPR012143; DiMe-aniline_mOase.
 IPR000960; Flavin_mOase.
 IPR020946; Flavin_mOase-like.
 IPR002257; Flavin_mOase_5.
 IPR016040; NAD(P)-bd_dom. 
Pfam
 PF00743; FMO-like 
SMART
  
PROSITE
  
PRINTS
 PR00370; FMOXYGENASE.
 PR01125; FMOXYGENASE5.