| Tag | Content |
|---|
| CPLM ID | CPLM-020008 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Thiamine transporter 2 |
Protein Synonyms/Alias | ThTr-2; ThTr2; Solute carrier family 19 member 3 |
Gene Name | Slc19a3 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 236 | SELFANSKNLEDREM | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Mediates high affinity thiamine uptake, propably via a proton anti-port mechanism. Has no folate transport activity (By similarity). |
Sequence Annotation | CARBOHYD 46 46 N-linked (GlcNAc...) (Potential).
CARBOHYD 358 358 N-linked (GlcNAc...) (Potential). |
Keyword | Complete proteome; Glycoprotein; Membrane; Reference proteome; Transmembrane; Transmembrane helix; Transport. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 488 AA |
Protein Sequence | MDSSCRTPPS NSWVYPTVIL CLFGFFSMFR PSEAFLIPFL SEPSKNLTSP EMTNEILPVW 60
TYSYLATLPP VFVLTDYLRY KPVIMLHVVA FATSYLFLLF GQGVMLMQTA EFFFGVVSAT 120
EIAYFAYIYS MVSPEHYQKV SSYCRSITLV AYTAGSVLAQ LLVSLTNLPY SSLFYISLAC 180
VSVAFFFSLF LPMPKKSMFF HAKSDRDDCP KPLEQCTVPK EAQSNRTHSE LFANSKNLED 240
REMSNPDPEN SALRHFAHWF QDLKECYSSK HLVYWSLWWA FATAGYNQIL NYVQVLWEHK 300
APSQDSSIYN GAVEAIATFG GALASFSVGY LKVNWDLLGE LGLAVFSAVI AGSLFLMNYS 360
RSIWVCYAGY LLVKSSYSFL ITIAVFQIAV NLSLERYALV FGIDTFIALV IQTIMTMIVV 420
DQRGLQLPVT TQFLVYGSYF AVIAGVFLMR SIYILCSAKC RKEVQNLATT RSPNEPHPQE 480
PSNVSTKF 488 |
Gene Ontology | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0005886; C:plasma membrane; IC:BHF-UCL. GO:0005542; F:folic acid binding; IEA:InterPro. GO:0008518; F:reduced folate carrier activity; IEA:InterPro. GO:0015403; F:thiamine uptake transmembrane transporter activity; IMP:BHF-UCL. GO:0015888; P:thiamine transport; ISO:MGI. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |