CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-033768
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Xeroderma pigmentosum complementation group C protein 
Protein Synonyms/Alias
  
Gene Name
  
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
44KQEETFAKGTCRPSAubiquitination[1]
178SSSSSSSKRGKKMCSubiquitination[1]
320NHPLYALKRHLLKYEubiquitination[1]
Reference
 [1] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965] 
Functional Description
  
Sequence Annotation
  
Keyword
  
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 508 AA 
Protein Sequence
GKKPSKERLT ADPGGSSETS SQVLENHTKP KTSKGTKQEE TFAKGTCRPS AKGKRNKGGR 60
KKRSKPSSSE EDEGPGDKQE KATQRRPHGR ERRVASRVSY KEESGSDEAG SGSDFELSSG 120
EASDPSDEDS EPGPPKQRKA PAPQRTKAGS KSASRTHRGS HRKDPSLPVA SSSSSSSKRG 180
KKMCSDGEKA EKRSIAGIDQ WLEVFCEQEE KWVCVDCVHG VVGQPLTCYK YATKPMTYVV 240
GIDSDGWVRD VTQRYDPVWM TVTRKCRVDA EWWAETLRPY QSPFMDREKK EDLEFQAKHM 300
DQPLPTAIGL YKNHPLYALK RHLLKYEAIY PETAAILGYC RGEAVYSRDC VHTLHSRDTW 360
LKKARVVRLG EVPYKMVKGF SNRARKARLA EPQLREENDL GLFGYWQTEE YQPPVAVDGK 420
VPRNEFGNVY LFLPSMMPIG CVQLNLPNLH RVARKLDIDC VQAITGFDFH GGYSHPVTDG 480
YIVCEEFKDV LLTAWENEQA VIERKEKE 508 
Gene Ontology
 GO:0005634; C:nucleus; IEA:InterPro.
 GO:0003684; F:damaged DNA binding; IEA:InterPro.
 GO:0006289; P:nucleotide-excision repair; IEA:InterPro. 
Interpro
 IPR004583; DNA_repair_Rad4.
 IPR018026; DNA_repair_Rad4_subgr.
 IPR018325; Rad4/PNGase_transGLS-fold.
 IPR018326; Rad4_beta-hairpin_dom1.
 IPR018327; Rad4_beta-hairpin_dom2.
 IPR018328; Rad4_beta-hairpin_dom3. 
Pfam
 PF10403; BHD_1
 PF10404; BHD_2
 PF10405; BHD_3
 PF03835; Rad4 
SMART
 SM01030; BHD_1
 SM01031; BHD_2
 SM01032; BHD_3 
PROSITE
  
PRINTS