CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-030792
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Transcription factor 12 
Protein Synonyms/Alias
 cDNA FLJ52589, highly similar to Transcription factor 12 
Gene Name
 TCF12 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
106MNSNLMGKTSERGSFubiquitination[1, 2]
147AQLSSSGKPGTAYYSubiquitination[1, 2]
393ENSLHSLKNRVEQQLubiquitination[2]
412QDAMSFLKDVCEQSRubiquitination[1]
517SSTDLNHKTQENYRGubiquitination[2]
591EDLNPEQKIEREKERubiquitination[1, 2]
618RDINEAFKELGRMCQubiquitination[1, 2]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 666 AA 
Protein Sequence
MNPQQQRMAA IGTDKELSDL LDFSAMFSPP VNSGKTRPTT LGSSQFSGSG TIHEMKQLNS 60
KARQKGQRIK GFTDSPHYSD HLNDSRLGAH EGLSPTPFMN SNLMGKTSER GSFSLYSRDT 120
GLPGCQSSLL RQDLGLGSPA QLSSSGKPGT AYYSFSATSS RRRPLHDSAA LDPLQAKKVR 180
KVPPGLPSSV YAPSPNSDDF NRESPSYPSP KPPTSMFAST FFMQDGTHNS SDLWSSSNGM 240
SQPGFGGILG TSTSHMSQSS SYGNLHSHDR LSYPPHSVSP TDINTSLPPM SSFHRGSTSS 300
SPYVAASHTP PINGSDSILG TRGNAAGSSQ TGDALGKALA SIYSPDHTSS SFPSNPSTPV 360
GSPSPLTGTS QWPRPGGQAP SSPSYENSLH SLKNRVEQQL HEHLQDAMSF LKDVCEQSRM 420
EDRLDRLDDA IHVLRNHAVG PSTSLPAGHS DIHSLLGPSH NAPIGSLNSN YGGSSLVASS 480
RSASMVGTHR EDSVSLNGNH SVLSSTVTTS STDLNHKTQE NYRGGLQSQS GTVVTTEIKT 540
ENKEKDENLH EPPSSDDMKS DDESSQKDIK VSSRGRTSST NEDEDLNPEQ KIEREKERRM 600
ANNARERLRV RDINEAFKEL GRMCQLHLKS EKPQTKLLIL HQAVAVILSL EQQVRERNLN 660
PKAACL 666 
Gene Ontology
  
Interpro
 IPR011598; bHLH_dom. 
Pfam
 PF00010; HLH 
SMART
 SM00353; HLH 
PROSITE
 PS50888; BHLH 
PRINTS