CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-016554
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Phostensin 
Protein Synonyms/Alias
 Protein phosphatase 1 F-actin cytoskeleton-targeting subunit; Protein phosphatase 1 regulatory subunit 18 
Gene Name
 Ppp1r18 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
437SRLFYGVKPGPGVGAacetylation[1]
Reference
 [1] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337] 
Functional Description
 May target protein phosphatase 1 to F-actin cytoskeleton (By similarity). 
Sequence Annotation
 MOD_RES 134 134 Phosphoserine.
 MOD_RES 174 174 Phosphoserine (By similarity).
 MOD_RES 194 194 Phosphoserine (By similarity).
 MOD_RES 198 198 Phosphothreonine (By similarity).
 MOD_RES 224 224 Phosphoserine (By similarity).
 MOD_RES 510 510 Phosphoserine.  
Keyword
 Actin-binding; Alternative splicing; Complete proteome; Cytoplasm; Cytoskeleton; Phosphoprotein; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 594 AA 
Protein Sequence
MTAIPDWKLQ LLARRRQEEA AVRGREKAER DRLSQMPAWK RGILERRRAK LGLPPGEGSP 60
VPGNAEAGPP DPDESAVLLE AIGPVHQNRF IQQERQRQQQ QQQQQRNEVL GDRKAGPLEV 120
LERRSSPGNL RDQSPKGRES REERLSPRES RDRRLVIGGA QESSSRSLRD WRQSPAEARD 180
LSSRPAEAQK WRLSPGETPE ESLRLAGSGD DSPKRKEVLE SILSPGEPGD QKASPTDVHK 240
WNLDSREPQK QSLIQLEATE WRLKSGEERK DYLEGCGREE EKLSSGIVPV TKEVQDITSS 300
EVETAEQRPT ESWKWTLNSG KARERTTWDI DTQTQKPDPP ASSEKHPGPS GMEAEEEAEK 360
EEAEAQSRPL RAQQNLCSGP SPLPPEHSGT EGSRQQEEEA AEPRPPTPAP LSPPPSAPTA 420
PQPSGDPLMS RLFYGVKPGP GVGAPRRSGH TFTVNPRRCA PPASPAPPVN PATADAAGSG 480
SGKKRYPTAE EILVLGGYLR LSRSCLVKGS PERHHKQLKI SFSETALETT YQYPSESSVL 540
EDLGPEPETP IAPLATQPDE EEEEEEEEEE LLLQPGLQGG LRTKALIVDE SCRR 594 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
 GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell. 
Interpro
 IPR025903; Phostensin/Taperin_N_dom.
 IPR025907; Phostensin/Taperin_PP1-bd_dom.
 IPR026671; PPP1R18/Tprn. 
Pfam
 PF13914; Phostensin
 PF13916; Phostensin_N 
SMART
  
PROSITE
  
PRINTS