UniProt Accession

 COX6_YEAST; P00427; D3DL00 

Genbank Protein ID

 M10138; U00062; AY558278; X14452; BK006934 

Genbank Nucleotide ID

 AAA66900.1; AAB68899.1; AAS56604.1; CAA32622.1; DAA06744.1 

Protein Name

 Cytochrome c oxidase subunit 6, mitochondrial 

Protein Synonyms/Alias

 Cytochrome c oxidase polypeptide VI 

Gene Name

 COX6 

Gene Synonyms/Alias

 YHR051W 

Created Date

 July 27, 2013 

Organism

 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 

NCBI Taxa ID

 559292 

Lysine Modification

Position	Peptide	Type	References
112	IRVFEALKYKVENED	acetylation	[1]
129	KAYLDELKDVRQELG	acetylation	[1]

Reference

 [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919] 

Functional Description

 This is the heme A-containing chain of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport. 

Sequence Annotation

  

Keyword

 Complete proteome; Direct protein sequencing; Heme; Iron; Membrane; Metal-binding; Mitochondrion; Mitochondrion inner membrane; Reference proteome; Transit peptide. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 148 AA 

Protein Sequence

Gene Ontology

 GO:0016021; C:integral to membrane; ISM:SGD.
 GO:0005751; C:mitochondrial respiratory chain complex IV; IPI:SGD.
 GO:0004129; F:cytochrome-c oxidase activity; IEA:InterPro.
 GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
 GO:0006123; P:mitochondrial electron transport, cytochrome c to oxygen; IDA:SGD. 

Interpro

 IPR003204; Cyt_c_oxidase_su5A/6. 

Pfam

 PF02284; COX5A 

SMART

  

PROSITE

  

PRINTS