| Tag | Content |
|---|
| CPLM ID | CPLM-016690 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Glycerophosphocholine phosphodiesterase GPCPD1 |
Protein Synonyms/Alias | Glycerophosphodiester phosphodiesterase 5; Preimplantation protein 4 |
Gene Name | Gpcpd1 |
Gene Synonyms/Alias | Gde5; Kiaa1434; Prei4 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 412 | FDQLQLLKLSHVTAL | ubiquitination | [1] | | 425 | ALKTKDRKQSLYEEE | ubiquitination | [1] | | 579 | PSYVQEAKAKGLVIF | ubiquitination | [1] | | 602 | PENRRKLKEFGVNGL | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | May be involved in the negative regulation of skeletal muscle differentiation, independently of its glycerophosphocholine phosphodiesterase activity. |
Sequence Annotation | DOMAIN 1 115 CBM20.
DOMAIN 326 616 GDPD.
REGION 88 89 Substrate binding (Potential).
BINDING 70 70 Substrate (Potential).
MOD_RES 611 611 Phosphotyrosine. |
Keyword | Alternative splicing; Complete proteome; Cytoplasm; Hydrolase; Phosphoprotein; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 675 AA |
Protein Sequence | MTPSQVTFEI RGTLLPGEVF AICGSCDALG NWNPQNAVAL INENETGDSV LWKAVIALNR 60
GVSVKYRYFR GCFLEPKTIG GPCQVIVHKW ETHLQPRSIT PLESEIIIDD GQFGIHNGVE 120
TLDSGWLTCQ TEIRLRLHFS EKPPVSISKK KFKKSRFRVK LTLEGLEEDE DDDDDKVSPT 180
VLHKMSNSLE ISLISDNEFK CRHSQPECGY GLQPDRWTEY SIQTMEPDNL ELIFDFFEED 240
LSEHVVQGDV LPGHVGTACL LSSTIAESGR SAGILTLPIM SRNSRKTIGK VRVDFIIIKP 300
LPGYSCSMQS SFSKYWKPRI PLDVGHRGAG NSTTTAKLAK VQENTIASLR NAASHGAAFV 360
EFDVHLSKDF VPVVYHDLTC CLTMKRKYEA DPVELFEIPV KELTFDQLQL LKLSHVTALK 420
TKDRKQSLYE EENFFSENQP FPSLKMVLES LPENVGFNIE IKWICQHRDG VWDGNLSTYF 480
DMNVFLDIIL KTVLENSGKR RIVFSSFDAD ICTMVRQKQN KYPILFLTQG KSDIYPELMD 540
LRSRTTPIAM SFAQFENILG INAHTEDLLR NPSYVQEAKA KGLVIFCWGD DTNDPENRRK 600
LKEFGVNGLI YDRIYDWMPE QPNIFQVEQL ERLKQELPEL KNCLCPTVSH FIPSSFCVEP 660
DIHVDANGID SVENA 675 |
Gene Ontology | GO:0005829; C:cytosol; TAS:Reactome. GO:0047389; F:glycerophosphocholine phosphodiesterase activity; IEA:EC. GO:0008889; F:glycerophosphodiester phosphodiesterase activity; IEA:InterPro. GO:2001070; F:starch binding; IEA:InterPro. GO:0006071; P:glycerol metabolic process; IEA:InterPro. GO:0006629; P:lipid metabolic process; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |