CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-007222
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Heat shock protein SSC3, mitochondrial 
Protein Synonyms/Alias
 Extracellular mutant protein 10 
Gene Name
 ECM10 
Gene Synonyms/Alias
 SSC3; YEL030W 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
69PSVVAFTKDGERLVGacetylation[1]
Reference
 [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919
Functional Description
 Plays a role in facilitating the assembly of some protein complexes inside the mitochondria. It may initiate the events that lead to refolding of imported precursors in the matrix space. 
Sequence Annotation
  
Keyword
 ATP-binding; Chaperone; Complete proteome; Mitochondrion; Mitochondrion nucleoid; Nucleotide-binding; Reference proteome; Transit peptide. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 644 AA 
Protein Sequence
MLPSWKAFKA HNILRILTRF QSTKIPDAVI GIDLGTTNSA VAIMEGKVPR IIENAEGSRT 60
TPSVVAFTKD GERLVGEPAK RQSVINSENT LFATKRLIGR RFEDAEVQRD INQVPFKIVK 120
HSNGDAWVEA RNRTYSPAQI GGFILNKMKE TAEAYLAKSV KNAVVTVPAY FNDAQRQATK 180
DAGQIIGLNV LRVVNEPTAA ALAYGLDKSE PKVIAVFDLG GGTFDISILD IDNGIFEVKS 240
TNGDTHLGGE DFDIYLLQEI ISHFKKETGI DLSNDRMAVQ RIREAAEKAK IELSSTLSTE 300
INLPFITADA AGPKHIRMPF SRVQLENITA PLIDRTVDPV KKALKDARIT ASDISDVLLV 360
GGMSRMPKVA DTVKKLFGKD ASKAVNPDEA VALGAAIQAA VLSGEVTDVL LLDVTPLSLG 420
IETLGGVFTK LIPRNSTIPN KKSQIFSTAA SGQTSVEVKV FQGERELVKD NKLIGNFTLA 480
GIPPAPKGTP QIEVTFDIDA NGIINVSAKD LASHKDSSIT VAGASGLSDT EIDRMVNEAE 540
RYKNQDRARR NAIETANKAD QLANDTENSI KEFEGKLDKT DSQRLKDQIS SLRELVSRSQ 600
AGDEVNDDDV GTKIDNLRTS SMKLFEQLYK NSDNPETKNG RENK 644 
Gene Ontology
 GO:0042645; C:mitochondrial nucleoid; IDA:SGD.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0042026; P:protein refolding; IGI:SGD.
 GO:0006626; P:protein targeting to mitochondrion; IGI:SGD. 
Interpro
 IPR012725; Chaperone_DnaK.
 IPR018181; Heat_shock_70_CS.
 IPR013126; Hsp_70_fam. 
Pfam
 PF00012; HSP70 
SMART
  
PROSITE
 PS00297; HSP70_1
 PS00329; HSP70_2
 PS01036; HSP70_3 
PRINTS
 PR00301; HEATSHOCK70.