CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-032156
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 DNA-binding protein RFX5 
Protein Synonyms/Alias
 cDNA FLJ52375, highly similar to DNA-binding protein RFX5 
Gene Name
 RFX5 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
321RLSSGALKVATLPLSmethylation[1]
321RLSSGALKVATLPLSubiquitination[2]
Reference
 [1] Mass spectrometry-based identification and characterisation of lysine and arginine methylation in the human proteome.
 Bremang M, Cuomo A, Agresta AM, Stugiewicz M, Spadotto V, Bonaldi T.
 Mol Biosyst. 2013 Jul 30;9(9):2231-47. [PMID: 23748837]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; DNA-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 576 AA 
Protein Sequence
MAEDEPDAKS PKTGGRAPPG GAEAGEPTTL LQRLRGTISK AVQNKVEGIL QDVQKFSDND 60
KLYLYLQLPS GPTTGDKRKY CESLACCRPL STANFGKIIR EIFPDIKARR LGGRGQSKYC 120
YSGIRRKTLV SMPPLPGLDL KGSESPEMGP EVTPAPRDEL VEAACALTCD WAERILKRSF 180
SSIVEVARFL LQQHLISARS AHAHVLKAMG LAEEDEHAPR ERSSKPKNGL ENPEGGAHKK 240
PERLAQPPKD LEARTGAGPL ARGERKKSVV ESSAPGANNL QVNALVARLP LLLPRAPRSL 300
IPPIPVSPPI LAPRLSSGAL KVATLPLSSR AGAPPAAVPI INMILPTVPA LPGPGPGPGR 360
APPGGLTQPR GTENREVGIG GDQGPHDKGV KRTAEVPVSE ASGQAPPAKA AKQDIEDTAS 420
DAKRKRGRPR KKSGGSGERN STPLKSAAAM ESAQSSRLPW ETWGSGGEGN SAGGAERPGP 480
MGEAEKGAVL AQGQGDGTVS KGGRGPGSQH TKEAEDKIPL VPSKVSVIKG SRSQKEAFPL 540
AKGEVDTAPQ GNKDLKEHVL QSSLSQEHKD PKATPP 576 
Gene Ontology
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro. 
Interpro
 IPR003150; DNA-bd_RFX.
 IPR011991; WHTH_DNA-bd_dom. 
Pfam
 PF02257; RFX_DNA_binding 
SMART
  
PROSITE
 PS51526; RFX_DBD 
PRINTS