CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-011801
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 GRIP domain-containing protein RUD3 
Protein Synonyms/Alias
 Golgin-related protein 1; Relieves USO1-1 transport defect protein 3 
Gene Name
 RUD3 
Gene Synonyms/Alias
 GRP1; YOR216C; YOR50-6 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
232IEALEDEKHDIIEKHacetylation[1]
458LISNNESKNSSAVSRubiquitination[2]
Reference
 [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919]
 [2] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301] 
Functional Description
 Invoved in the structural organization of the cis-Golgi and in vesicle targeting/fusion stages of ER to Golgi transport. 
Sequence Annotation
 DOMAIN 401 452 GRIP.
 MOD_RES 55 55 Phosphoserine.
 MOD_RES 64 64 Phosphoserine.
 MOD_RES 468 468 Phosphoserine.  
Keyword
 Coiled coil; Complete proteome; ER-Golgi transport; Golgi apparatus; Phosphoprotein; Reference proteome; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 484 AA 
Protein Sequence
MGKNKKKTGK KAKSHPHVED VDETVNKPEE IINSVNVTVP PKMSTDPEAD GIVASPDDEG 60
KDLSEGVDKQ KVNDGLTVDT INPLEDKKAG DEMKELREEI ERLKLELSHK KDQETPNEDF 120
KNELANVIKE RDEFKTQYDT LLSKISSMKS IFNKMKEAQK QLEEVQEQLT EYESQNLKLK 180
KKLEATKTEN SELQSTIVTL NTELENLEKE QESTEEVFLE YESRIEALED EKHDIIEKHS 240
KELNTYRKEK DQLNLQVQEL MIILENNKQD ISDLRTERDE LRQALESHEK EKAVLKNSLN 300
DLELKIEEVD NKREEEARER DQEVKSLRSQ LDTEIETHNN DTEALESMKK QLEAMKEDAS 360
MKEKYEEESK QHILQIGKLR HEAIILNEHL TKALAMLKKS SDSESVDKEL ISNLLISFVS 420
IPRADPRKFE VLELLSNFLN WDEDKKQQAG LISNNESKNS SAVSRTESFV SLWTNYLEKE 480
SEKD 484 
Gene Ontology
 GO:0005794; C:Golgi apparatus; NAS:SGD.
 GO:0005796; C:Golgi lumen; IEA:UniProtKB-SubCell.
 GO:0006888; P:ER to Golgi vesicle-mediated transport; IGI:SGD.
 GO:0000042; P:protein targeting to Golgi; IEA:InterPro. 
Interpro
 IPR019459; GRAB.
 IPR000237; GRIP. 
Pfam
 PF10375; GRAB 
SMART
  
PROSITE
 PS50913; GRIP 
PRINTS