UniProt Accession

 AIPL1_HUMAN; Q9NZN9; D3DTM4; Q6ZZB6; Q8N6A0; Q9H873; Q9NS10 

Genbank Protein ID

 AF180472; AF148864; AF525970; AK023970; AJ633677; AB593053; AB593054; AC055872; CH471108; CH471108; CH471108; CH471108; BC012055 

Genbank Nucleotide ID

 AAF26708.1; AAF74023.1; AAM88405.1; BAB14744.1; CAG17882.1; BAJ84000.1; BAJ84001.1; EAW90310.1; EAW90312.1; EAW90313.1; EAW90314.1; AAH12055.1 

Protein Name

 Aryl-hydrocarbon-interacting protein-like 1 

Protein Synonyms/Alias

  

Gene Name

 AIPL1 

Gene Synonyms/Alias

 AIPL2 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
214	CLRNLQTKEKPWEVQ	ubiquitination	[1]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 

Functional Description

 May be important in protein trafficking and/or protein folding and stabilization. 

Sequence Annotation

 DOMAIN 53 145 PPIase FKBP-type.
 REPEAT 178 211 TPR 1.
 REPEAT 230 263 TPR 2.
 REPEAT 264 297 TPR 3.  

Keyword

 Alternative splicing; Complete proteome; Cytoplasm; Disease mutation; Leber congenital amaurosis; Nucleus; Polymorphism; Reference proteome; Repeat; Sensory transduction; TPR repeat; Vision. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 384 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IDA:MGI.
 GO:0005634; C:nucleus; IDA:MGI.
 GO:0001917; C:photoreceptor inner segment; IEA:Compara.
 GO:0001918; F:farnesylated protein binding; IDA:MGI.
 GO:0051082; F:unfolded protein binding; TAS:ProtInc.
 GO:0043066; P:negative regulation of apoptotic process; IEA:Compara.
 GO:0007603; P:phototransduction, visible light; IEA:Compara.
 GO:0018343; P:protein farnesylation; IDA:MGI.
 GO:0006457; P:protein folding; IEA:InterPro.
 GO:0030823; P:regulation of cGMP metabolic process; IEA:Compara.
 GO:0001895; P:retina homeostasis; IEA:Compara.
 GO:0007601; P:visual perception; TAS:ProtInc. 

Interpro

 IPR001179; PPIase_FKBP_dom.
 IPR013026; TPR-contain_dom.
 IPR011990; TPR-like_helical.
 IPR013105; TPR_2. 

Pfam

 PF00254; FKBP_C
 PF07719; TPR_2 

SMART

  

PROSITE

 PS50059; FKBP_PPIASE
 PS50005; TPR
 PS50293; TPR_REGION 

PRINTS