CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-026371
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Importin-4 
Protein Synonyms/Alias
 Ipo4 protein 
Gene Name
 Ipo4 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
205LARMLVPKVVTALRTubiquitination[1]
762PAYMQAVKVERERPVubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Nucleus; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 818 AA 
Protein Sequence
MEPAGLEQIL KELLLPDTER IRRATEQLQT ILRDPAALPA LFDLLATATD SQIRQFAAVL 60
TRRRLNNRWR RLAPEQRESL KSLVLTALQK ETVHSVSVSL AQLSATIFRK EGLQGWPQFM 120
NLLQHSTHSS HSPEKEVGLL LLSVVVSSQP EAFHAHQHEL LQLLNETLSD VSFPGVLFYS 180
LRTLTAIARY VRPDDVSLAR MLVPKVVTAL RTLIPLDEVK ACEALEALDE MLETELPIIN 240
PHLSEVLTFC LEVAKNVALG EPLRVRVLCC LTFLVKVKSK ALLKNRLVPP LLHALFPLMA 300
AEPPMGQLDP EDQDSDDDDL EIGLMGETPK HFAVQVVDML ALHLPPEKLC PHVMPMLEEA 360
LRSEDPYQRK AGFLVLAVLS DGAGDHIRQR LLYPLLQIVC KGLDDPSQIV RNAALFALGQ 420
FSENLQPHIS SYSEEVMPLL LSYLKSVPMG NTHHLAKACY ALENFVENLG PKVQPYLPEL 480
MECMLQPLKN PSKARTKELA VSAIGAIATA AQDSLLPYFP TIMDLLREFL LTGHEDFHLV 540
QIQSLETLGV LARALGESMK PLAEECCQLG LGLCIHIDDP DVRRCTYSLF AALSGLMGEG 600
LGPYLPQITT LMLLSLRSTE GIVPQYDGIS SFLLFDDDSE AEEEEELMDE DMEEEGDDSE 660
ISGYSVENAF FDEKEDTCTA LGEISMNTCV AFLPFMDATF DEVYKLLECP HMNVRKSAYE 720
ALGQFCCALH KASQRSSSDP SSSPVLQTSL ARVMPAYMQA VKVERERPVV MAVLESLTGV 780
LRTCGSLALQ PPGRLSELCN VLKAVLQKKE QVGDLKLS 818 
Gene Ontology
 GO:0005643; C:nuclear pore; IEA:InterPro.
 GO:0008565; F:protein transporter activity; IEA:InterPro.
 GO:0006610; P:ribosomal protein import into nucleus; ISA:MGI.
 GO:0042254; P:ribosome biogenesis; ISA:MGI. 
Interpro
 IPR011989; ARM-like.
 IPR016024; ARM-type_fold.
 IPR000357; HEAT.
 IPR001494; Importin-beta_N. 
Pfam
 PF02985; HEAT
 PF03810; IBN_N 
SMART
 SM00913; IBN_N 
PROSITE
 PS50166; IMPORTIN_B_NT 
PRINTS